Lenvatinib Impurity 100 CAS 2712290-12-3
| CAS No. | 2712290-12-3 |
| Molecular Formula | C17H13ClN2O4 |
| Molecular Weight | 344.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lenvatinib Impurity 100 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lenvatinib Impurity 100 (CAS 2712290-12-3) is a certified pharmaceutical impurity reference standard with the molecular formula C17H13ClN2O4 and a molecular weight of 344.75 g/mol.
Lenvatinib Impurity 100 (C17H13ClN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lenvatinib Impurity 100 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H13ClN2O4 |
| Molecular Weight | 344.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Lenvatinib Standards
- Lenvatinib Impurity 57 (CAS CATO-C4X-114057)
- Lenvatinib Impurity 143 (CAS CATO-C4X-1140143)
- Lenvatinib Impurity 146 (CAS CATO-C4X-1140146)
- Lenvatinib impurity 167 (CAS CATO-C4X-1140167)
- Lenvatinib impurity 168 (CAS CATO-C4X-1140168)
- Lenvatinib Impurity 40 (CAS 417722-93-1)
- Lenvatinib Impurity 63 (CAS 2380197-89-5)
- Lenvatinib Impurity 32 (CAS 205448-64-2)
Recommended Standards
- N-(4-chlorobenzyl)-2-((1,3-dioxoisoindolin-2-yl)oxy)acetamide (CAS 339105-85-0)
- 6-(Benzyloxy)-4-chloro-7-methoxy-3-nitroquinoline (CAS 909912-12-5)
- Bosentan Impurity 22 (CAS CATO-C4X-156422)
- 4-(4-Chlorophenyl)-5-methyl-2-(4-nitrobenzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860786-63-6)
- Alogliptin Impurity 90 (CAS CATO-C4X-109990)
- R-Salbutamol Glyoxal Impurity (CAS CATO-C4X-1176205)
- Irinotecan Impurity 65 (CAS CATO-C4X-166765)
- 4,8-Dibromodecahydro-2,8,4,6-(epibutane[1,2,3,4]tetrayl)naphthalene (CAS 32401-10-8)
- 5-Methoxybicyclo[4.2.0]octa-1,3,5-trien-7-one (CAS 66947-60-2)
- Ethyl 2-bromobutanoat (CAS 533-68-6)
- Chloroprallethrin (CAS 250346-55-5)
- 3-bromoquinoline-2-carboxylic acid (CAS 1564924-85-1)
- 2-Methoxy-3-methylbenzonitrile (CAS 53078-68-5)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com