Lenvatinib Impurity 63 CAS 2380197-89-5
| CAS No. | 2380197-89-5 |
| Molecular Formula | C17H14ClN3O3 |
| Molecular Weight | 343.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lenvatinib Impurity 63.
CATO supplies Lenvatinib Impurity 63 (CAS 2380197-89-5), a pharmacopoeial impurity reference standard (molecular formula C17H14ClN3O3, MW 343.76 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C17H14ClN3O3, Lenvatinib Impurity 63 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 343.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lenvatinib Impurity 63 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H14ClN3O3 |
| Molecular Weight | 343.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Lenvatinib Standards
- Lenvatinib Impurity 143 (CAS CATO-C4X-1140143)
- Lenvatinib Impurity 146 (CAS CATO-C4X-1140146)
- Lenvatinib impurity 167 (CAS CATO-C4X-1140167)
- Lenvatinib impurity 168 (CAS CATO-C4X-1140168)
- Lenvatinib Impurity 40 (CAS 417722-93-1)
- Lenvatinib Impurity 100 (CAS 2712290-12-3)
- Lenvatinib Impurity 57 (CAS CATO-C4X-114057)
- Lenvatinib Impurity 32 (CAS 205448-64-2)
Recommended Standards
- Roxadustat Impurity 30 (CAS CATO-C4X-221330)
- Roxadustat Impurity 53 (CAS CATO-C4X-221353)
- 2-((6-(1H-Pyrazol-1-yl)pyridazin-3-yl)oxy)-N-(2-chlorobenzyl)acetamide (CAS 1428375-86-3)
- 1-Boc-4-(6-Chloro-5-nitro-4-pyrimidinyl)piperazine (CAS 147539-23-9)
- Retigabine Impurity 1 (CAS CATO-C4X-13141)
- Ilaprazole Impurity 40 (CAS 102625-96-7)
- Tadalafil Impurity N98 (CAS 1795790-92-9)
- 2-(4-Chloro-3-fluorophenoxy)-3-methylquinoxaline (CAS 477870-89-6)
- 5-Allylpyrazin-2-amine (CAS 710323-25-4)
- 5-(3-Formylphenyl)-2-hydroxyisonicotinic acid (CAS 1261945-51-0)
- 8-((3-Methoxyphenyl)thio)-1H-purin-6-amine (CAS 696574-58-0)
- Virginiamycin (CAS 11006-76-1)
- 1-(2-Chloropyridin-4-yl)-2,2,2-trifluoroethanone (CAS 898784-96-8)
- Semaglutide impurity 267 (CAS CATO-C4X-2226267)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com