Diclofenac EP Impurity C CAS 27204-57-5
| CAS No. | 27204-57-5 |
| Molecular Formula | C13H11Cl2NO |
| Molecular Weight | 268.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Diclofenac EP Impurity C.
As a process- or degradation-related impurity, Diclofenac EP Impurity C (CAS 27204-57-5, C13H11Cl2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Diclofenac EP Impurity C is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 268.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Diclofenac EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11Cl2NO |
| Molecular Weight | 268.14 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Diclofenac Standards
- Diclofenac Impurity 18 (CAS 60805-30-3)
- Diclofenac Impurity 20 (CAS 60805-31-4)
- Diclofenac Impurity 11 (CAS 51550-51-7)
- Diclofenac EP Impurity B (CAS 22121-58-0)
- Diclofenac potassium Impurity 7 (CAS CATO-C4X-10517)
- Diclofenac impurity 5 (CAS CATO-C4X-16145)
- Diclofenac Impurity 20 (CAS 15362-44-4)
- Diclofenac sodium Impurity 7 (CAS 127792-34-1)
Recommended Standards
- tert-Butyl 7,7-dichloro-2-oxa-5-azabicyclo[4.1.0]heptane-5-carboxylate (CAS 2138112-98-6)
- 1-[(2-bromophenyl)methyl]piperidin-4-one (CAS 1016770-11-8)
- ethyl 2,4-dichloropyrrolo[2,1-f][1,2,4]triazine-5-carboxylate (CAS 2069971-89-5)
- 1-(4-Bromo-3-methylphenyl)piperidin-2-one (CAS 1017029-00-3)
- Nimodipine Impurity N15 (CAS 101072-61-1)
- N-nitroso Peramivir Impurity100 (CAS CATO-C4X-1833100)
- Ebastine Impurity 13 (CAS 97928-34-2)
- 5,7-dihydro-4H-spiro[1,3-benzothiazole-6,1’-cyclohexane]-2-amine (CAS 188051-12-9)
- N-(4-methylbenzyl)hexan-2-amine (CAS 1157130-40-9)
- (4-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)(isoxazol-5-yl)methanone (CAS 1210264-75-7)
- 2-methyl-1,2,3,4-tetrahydrophthalazine hydrochloride (CAS 20072-58-6)
- 4-Ethoxy-2,3-difluoro-6-methylphenol (CAS 886037-78-1)
- 1-{2-[6-(3,4-dimethoxyphenyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-2,5-dimethyl-1H-pyrrole (CAS 439111-91-8)
- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com