Ethyl 3-chloro-8-fluoroquinoline-6-carboxylate CAS 2721375-38-6
| CAS No. | 2721375-38-6 |
| Molecular Formula | C12H9ClFNO2 |
| Molecular Weight | 253.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Ethyl 3-chloro-8-fluoroquinoline-6-carboxylate (CAS 2721375-38-6), a certified reference material (molecular formula C12H9ClFNO2, MW 253.66 g/mol) for analytical method development and quality control.
Ethyl 3-chloro-8-fluoroquinoline-6-carboxylate (C12H9ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Ethyl 3-chloro-8-fluoroquinoline-6-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9ClFNO2 |
| Molecular Weight | 253.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Methyl 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate (CAS 100784-27-8)
- 3-(2-Chloro-6-fluoroquinolin-3-yl)propanoic acid (CAS 1017378-60-7)
- 1-(2-Chloro-6-fluorobenzyl)-1H-pyrrole-3-carboxylic acid (CAS 1500987-02-9)
- 1-(2-Chloro-4-fluorobenzyl)-1H-pyrrole-3-carboxylic acid (CAS 1538774-36-5)
- 2-Chloro-5-fluoro-n-(2-methoxyphenyl)-4-pyrimidinamine (CAS 727422-01-7)
- 2-Chloro-n-(3-cyclopropyl-1h-pyrazol-5-yl)-5-fluoropyrimidin-4-amine (CAS 851434-98-5)
- 4-Chloro-1-(4-fluorophenyl)-N-methyl-1H-pyrazole-5-carboxamide (CAS 318949-30-3)
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Recommended Standards
- 6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonyl chloride (CAS 926246-59-5)
- 5-Chloropyrazolo[1,5-a]thieno[2,3-e]pyrimidine-3-carboxylic acid (CAS 680210-93-9)
- Ethyl 4-chloro-7-fluoroquinoline-3-carboxylate (CAS 26893-13-0)
- Ethyl 4-Chloro-8-fluoroquinoline-3-carboxylate (CAS 56824-90-9)
- (4,6-Dichloropyrimidin-2-yl)boronic acid (CAS 1097652-85-1)
- 6-Fluoro-4-(trifluoromethyl)-quinoline-2-carbohydrazide (CAS 1116339-62-8)
- 3-Bromopyridine-2,5-dicarboxylic acid (CAS 1260664-10-5)
- 2,2,2-Trichloro-1-morpholinoethan-1-one (CAS 13306-60-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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