Baclofen EP Impurity C (Mixture of Diastereomers) CAS 2726264-10-2
| CAS No. | 2726264-10-2 |
| Molecular Formula | C21H22Cl2N2O5 |
| Molecular Weight | 453.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Baclofen EP Impurity C (Mixture of Diastereomers) (C21H22Cl2N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Baclofen EP Impurity C (Mixture of Diastereomers) (CAS 2726264-10-2) is a certified pharmaceutical impurity reference standard with the molecular formula C21H22Cl2N2O5 and a molecular weight of 453.32 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H22Cl2N2O5 |
| Molecular Weight | 453.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Baclofen Standards
- Baclofen impurity 71（Z-Isomer） (CAS CATO-C4X-101271)
- Baclofen EP Impurity H (CAS CATO-C4X-101252)
- Baclofen Impurity 69 (CAS CATO-C4X-101269)
- Baclofen impurity 72 (CAS CATO-C4X-101272)
- Baclofen Impurity 67 (CAS CATO-C4X-101267)
- Baclofen impurity 73（E-Isomer） (CAS CATO-C4X-101273)
- Baclofen impurity 11 (CAS CATO-C4X-101211)
- Baclofen impurity 15 (CAS CATO-C4X-101215)
Recommended Standards
- 3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-1-(4-methoxybenzoyl)-1H-pyrazole (CAS 477711-60-7)
- Dapagliflozin 4-Bromo Analog (CAS 1807632-95-6)
- (3-(3-((2,4-Dichlorobenzyl)oxy)phenyl)-1H-pyrazol-1-yl)(4-methoxyphenyl)methanone (CAS 477712-62-2)
- tert-Butyl 4-(4-bromo-2-(ethoxycarbonyl)benzofuran-5-yl)piperazine-1-carboxylate (CAS 1192170-25-4)
- Mirogabalin Impurity 99 (CAS CATO-C4X-292499)
- Granisetron Impurity 19 (CAS CATO-C4X-197019)
- Moxifloxacin Impurity 109 (CAS 1641561-55-8)
- 1,3,6,7-Tetramethylpyrrolo[1,2-a]pyrazine (CAS 95407-84-4)
- n-(5-Bromopyrazin-2-yl)-3-chlorobenzenesulfonamide (CAS 1394709-62-6)
- Ethyl 2-(3-ethoxyphenyl)-2-oxoacetate (CAS 1256480-97-3)
- (2E,4E)-2,4-Hexadecadienoic acid (CAS 59404-48-7)
- 2-(4-(Isopropylthio)phenyl)-N-((1-(thiophen-2-yl)cyclopropyl)methyl)acetamide (CAS 1210882-72-6)
- 2-Chloro-1-(3-((cyclopropylmethyl)amino)piperidin-1-yl)ethanone (CAS 1353988-93-8)
- Biotinyl-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 213779-13-6)
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