Baclofen Impurity 67 CAS CATO-C4X-101267
| CAS No. | CATO-C4X-101267 |
| Molecular Formula | C21H24Cl2N2O3 |
| Molecular Weight | 423.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Baclofen Impurity 67 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Baclofen Impurity 67 (CAS CATO-C4X-101267), a pharmacopoeial impurity reference standard (molecular formula C21H24Cl2N2O3, MW 423.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Baclofen Impurity 67 (C21H24Cl2N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H24Cl2N2O3 |
| Molecular Weight | 423.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Baclofen Standards
- Baclofen impurity 73（E-Isomer） (CAS CATO-C4X-101273)
- Baclofen impurity 72 (CAS CATO-C4X-101272)
- Baclofen EP Impurity H (CAS CATO-C4X-101252)
- Baclofen Impurity 69 (CAS CATO-C4X-101269)
- Baclofen impurity 11 (CAS CATO-C4X-101211)
- Baclofen impurity 71（Z-Isomer） (CAS CATO-C4X-101271)
- Baclofen EP Impurity C (Mixture of Diastereomers) (CAS 2726264-10-2)
- Baclofen impurity 15 (CAS CATO-C4X-101215)
Recommended Standards
- 5-methylnaphthalene-1-carboxylic acid (CAS 4527-60-0)
- 9-Bromo-16α,17-epoxy-11β-hydroxyprogesterone (CAS 110053-24-2)
- 5,5'-(5-Aminopyrimidine-4,6-diyl)diisophthalic acid (CAS 1980832-02-7)
- [4-[Bis(diethoxyphosphoryl)methyl]phenyl] carbamate (CAS 117758-87-9)
- Gemcitabine Impurity 37 (CAS 122111-08-4)
- Methyl 5-acetylthiophene-2-carboxylate(Arotinolol Impurity 6) (CAS 4101-81-9)
- Ezetimibe Impurity 6 (CAS CATO-C4X-10986)
- 2-Chloro-N-methyl-3-oxobutanamide (CAS 4116-10-3)
- 2-Hydroxy-6-methylbenzenesulfonamide (CAS 43059-22-9)
- 8-Bromo-6-chloro-2H-chromene-3-carbonitrile (CAS 885271-10-3)
- Raltitrexed Impurity 15 (CAS CATO-C4X-138615)
- 4-(2-Pyrrolidin-1-yl-ethoxy)-benzoic acid 69731-93-7 8341AE C13H17NO3 (CAS 69731-93-7)
- (E)-2-(Benzo[d]thiazol-2-yl)-3-phenylacrylonitrile (CAS 157946-21-9)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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