3-chloro-1,2-oxazole-5-carboxamide CAS 272773-14-5
| CAS No. | 272773-14-5 |
| Molecular Formula | C4H3ClN2O2 |
| Molecular Weight | 146.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-chloro-1,2-oxazole-5-carboxamide (C4H3ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 3-chloro-1,2-oxazole-5-carboxamide (CAS 272773-14-5), a certified reference material (molecular formula C4H3ClN2O2, MW 146.53 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-chloro-1,2-oxazole-5-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H3ClN2O2 |
| Molecular Weight | 146.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- 5-Chloro-1H-pyrazole-4-carboxylic acid (CAS 1186049-67-1)
- 6-Chloro-4-hydroxypyridazin-3(2H)-one (CAS 17276-75-4)
- 2-Chloro-1-(1,2,5-oxadiazol-3-yl)ethanone (CAS 1803581-79-4)
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Recommended Standards
- 2-Chlorofuran-3-carboxylic acid (CAS 31491-45-9)
- 3-chlorofuran-2-carboxylic acid (CAS 66204-31-7)
- 4-Chloropyrazole-3-carboxylic Acid (CAS 84547-87-5)
- 4-methyl-1,2,5-oxadiazole-3-carbonyl chloride (CAS 15323-68-9)
- ETHYL 3-(4-HYDROXY-3-METHOXYPHENYL)-3-OXOPROPANOATE (CAS 56222-44-7)
- 3-(2,2-Dimethylmorpholino)-5,6-dimethylpyridazine-4-carbonitrile (CAS 1292366-46-1)
- (2Z)-1-[1-(4-Chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-3-hydroxybut-2-en-1-one (CAS 129302-13-2)
- 2,4-Dichloro-4'-(difluoromethoxy)-2'-fluoro-1,1'-biphenyl (CAS 1361765-52-7)
- (1S,4R)-Acetic acid 4-tert-butoxycarbonylamino-cyclopent-2-enyl ester (CAS 189625-14-7)
- 4-(Ethylsulfonyl)-3-(o-tolyl)-1H-pyrazole (CAS 1710416-93-5)
- N-Cyclobutyl-5-fluoropyrimidin-2-amine (CAS 1565730-62-2)
- 2-((3-Bromophenyl)amino)-4-methylthiazole-5-carboxylic acid (CAS 1071328-75-0)
- 2-Chloro-N-(2,4,6-trichlorophenyl)acetamide (CAS 22303-34-0)
- Lixisenatide (CAS 320367-13-3)
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