2-Chloro-1H-imidazole-4-carboxylic Acid CAS 944905-33-3
| CAS No. | 944905-33-3 |
| Molecular Formula | C4H3ClN2O2 |
| Molecular Weight | 146.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-1H-imidazole-4-carboxylic Acid (CAS 944905-33-3), molecular formula C4H3ClN2O2 and molecular weight 146.53 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloro-1H-imidazole-4-carboxylic Acid is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 146.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-1H-imidazole-4-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H3ClN2O2 |
| Molecular Weight | 146.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-1H-pyrazole-4-carboxylic acid (CAS 1186049-67-1)
- 6-Chloro-4-hydroxypyridazin-3(2H)-one (CAS 17276-75-4)
- 2-Chloro-1-(1,2,5-oxadiazol-3-yl)ethanone (CAS 1803581-79-4)
- 2-Chloro-3-nitro-1H-pyrrole (CAS 80947-09-7)
- 3-chloro-1,2-oxazole-5-carboxamide (CAS 272773-14-5)
- 3-Chloro-4-methylfuran-2,5-dione (CAS 57547-55-4)
- 4-Chloro-1,2-dihydropyridazine-3,6-dione (CAS 5397-64-8)
- 4-Chloro-5-hydroxypyridazin-3(2H)-one (CAS 64178-58-1)
Recommended Standards
- 2-Chlorofuran-3-carboxylic acid (CAS 31491-45-9)
- 4-methyl-1,2,5-oxadiazole-3-carbonyl chloride (CAS 15323-68-9)
- 3-Chloropyrazole-4-carboxylic Acid (CAS 134589-59-6)
- 4,6-Dihydroxy-5-chloropyrimidine (CAS 1193-56-2)
- 4-Chloro-1-(trimethylsilyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 257298-06-9)
- Methyl 3,5-difluoro-4-formylbenzoate (CAS 1415124-73-0)
- Methyl 2-methyl-3-(trimethylsilyl)propanoate (CAS 18388-42-6)
- N1,N1-dimethyl-1-(3-methylthiophen-2-yl)ethane-1,2-diamine (CAS 954573-16-1)
- 3-(4-Chlorophenyl)-3-(1h-pyrrol-1-yl)propanoic acid (CAS 404869-77-8)
- 2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-D-glucono-1,5-lactone (CAS 34051-37-1)
- N,N'-(3-Cyclopropoxypyridine-2,5-diyl)dimethanesulfonamide (CAS 1243466-56-9)
- Methyl 4,6-difluoro-1H-indazole-3-carboxylate (CAS 1360973-23-4)
- 2-(4-Fluorophenyl)thiazole (CAS 1005196-13-3)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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