Metaraminol Impurity 2(L-(+)-Tartaric Acid) CAS 27303-40-8
| CAS No. | 27303-40-8 |
| Molecular Formula | C9H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metaraminol Impurity 2(L-(+)-Tartaric Acid).
Metaraminol Impurity 2(L-(+)-Tartaric Acid) (CAS 27303-40-8) is a certified pharmaceutical impurity reference standard with the molecular formula C9H13NO2C4H6O6 and a molecular weight of 317.29 g/mol.
Metaraminol Impurity 2(L-(+)-Tartaric Acid) (C9H13NO2C4H6O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H13NO2 C4H6O6 |
| Molecular Weight | 317.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 1 |
Related Metaraminol Standards
- Metaraminol Impurity 12 (CAS 130826-91-4)
- Metaraminol Impurity 15 (CAS 13103-80-5)
- Metaraminol impurity 104 (CAS 1379208-51-1)
- Metaraminol Impurity 68 (CAS 1379208-51-1（free base）)
- Metaraminol Impurity 89 (CAS 1602857-88-4)
- Metaraminol Impurity 20 (CAS 1602857-90-8)
- Metaraminol Impurity 21 (CAS 1602857-94-2)
- Metaraminol Impurity 36 (CAS 1700-37-4)
Recommended Standards
- Methotrexate Impurity 43 (CAS 79974-20-2)
- Gefitinib Impurity 89 (CAS CATO-C4X-111789)
- Droperidol EP Impurity B (CAS 1026015-45-1)
- tert-Butyl 4-((3-fluorophenyl)amino)piperidine-1-carboxylate (CAS 679409-18-8)
- Ethyl 3-bromo-5-chloro-2-hydroxybenzoate (CAS 773134-85-3)
- (S)-1-(4-Pyridyl)ethylamine (CAS 27854-96-2)
- (S)-6-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 136759-41-6)
- Ytterbium(III) chloride (CAS 10361-91-8)
- Fezolinetant (CAS 1629229-37-3)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
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