(R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid CAS 273222-07-4
| CAS No. | 273222-07-4 |
| Molecular Formula | C20H17F2NO4 |
| Molecular Weight | 373.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid (CAS 273222-07-4), molecular formula C20H17F2NO4 and molecular weight 373.35 g/mol, is a CATO reference standard with documented purity and traceability.
(R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid (C20H17F2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures (R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H17F2NO4 |
| Molecular Weight | 373.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-difluorocyclobutanecarboxylic acid (CAS 1936532-04-5)
- (S)-1-Fmoc-4,4-difluoropyrrolidine-2-carboxylic Acid (CAS 203866-21-1)
- 3,3,3-Trifluoro-2-hydroxy-2-methyl-N-(4-(phenylsulfonyl)phenyl)propanamide (CAS 147695-92-9)
- 1-(Tert-butyl) 2-methyl (2S,4S)-4-(3,4-difluoro-5-hydroxyphenoxy)pyrrolidine-1,2-dicarboxylate (CAS 2442511-27-3)
- tert-Butyl 4',6'-dihydrospiro[cyclopropane-1,7'-pyrazolo[4,3-c]pyridine]-5'(2'H)-carboxylate (CAS 1028320-38-8)
- 4,6-Dichloro-2-(2,2-difluoro-propoxy)-pyrimidine-5-carbonitrile (CAS 1965309-21-0)
- 1-Methylimidazole-4-carbaldehyde (CAS 17289-26-8)
- 5-Chloro-2-[(2,4-dimethylphenyl)sulfanyl]aniline (CAS 727983-41-7)
- 2-(2,5-Dimethyl-1h-pyrrol-1-yl)-3-phenylpropanoic acid (CAS 130016-75-0)
- 2,2,2-trifluoroethyl N-(3-chloro-1-benzothiophen-2-yl)carbamate (CAS 1311313-98-0)
- 2-(Phenylamino)isoindoline-1,3-dione (CAS 4870-16-0)
- 6,8-Dichloro-2-[(1E)-3-methylbut-1-en-1-yl]-4H-3,1-benzoxazin-4-one (CAS 946387-00-4)
- 2-[(2-Benzimidazolyl)methyl]benzothiazole (CAS 66557-64-0)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com