Rilpivirine Impurity 14 CAS 2734549-19-8

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.2734549-19-8
Molecular FormulaC22H18N6O
Molecular Weight382.42 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rilpivirine Impurity 14 CAS 2734549-19-8 chemical structure

Description

CATO supplies Rilpivirine Impurity 14 (CAS 2734549-19-8), a pharmacopoeial impurity reference standard (molecular formula C22H18N6O, MW 382.42 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Rilpivirine Impurity 14 (C22H18N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Rilpivirine Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC22H18N6O
Molecular Weight382.42 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Nitrogen Atoms6

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