Rilpivirine Impurity 12 CAS 1446439-51-5
| CAS No. | 1446439-51-5 |
| Molecular Formula | C22H20N6O |
| Molecular Weight | 384.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Rilpivirine Impurity 12 (CAS 1446439-51-5), a pharmacopoeial impurity reference standard (molecular formula C22H20N6O, MW 384.43 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Rilpivirine Impurity 12 (C22H20N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rilpivirine Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H20N6O |
| Molecular Weight | 384.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 6 |
Related Rilpivirine Standards
- Rilpivirine Amide (CAS 500288-66-4)
- Rilpivirine Impurity 14 (CAS 2734549-19-8)
- Rilpivirine Impurity 15 (CAS CATO-C4X-136315)
- Rilpivirine-d6 (CAS 1312424-26-2)
- Rac-Rilpivirine (CAS 620622-82-4)
- Rilpivirine (CAS 500287-72-9)
- Rilpivirine (Z-Isomer) (CAS 500287-94-5)
- Rilpivirine impurity 10 (CAS CATO-C4X-136310)
Recommended Standards
- Dabigatran Impurity 133 (CAS CATO-C4X-1089133)
- Istradefylline Impurity 6 (CAS CATO-C4X-10616)
- Cefoxitin EP Impurity A (CAS 54333-94-7)
- Istradefylline impurity 31 (CAS CATO-C4X-106131)
- Valsartan Impurity 145 (CAS 2624122-60-5)
- Metaraminol Impurity N2 (CAS 693772-30-4)
- Tirofiban Impurity 44 (CAS CATO-C4X-125444)
- N-(2-(3-(Pyridin-2-yl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)ethyl)thiophene-2-sulfonamide (CAS 1797258-92-4)
- 3-(4-Ethoxybenzenesulfonamido)propanoic acid (CAS 732288-02-7)
- n-(1-Cyclopropylethyl)-2-isopropylaniline (CAS 1019583-41-5)
- (5-(Benzylsulfonyl)-1H-1,2,4-triazol-1-yl)methanol (CAS 32550-64-4)
- 2-Iodo-1H-pyrrolo[3,2-b]pyridine (CAS 1227268-72-5)
- 2-Bromo-4-Methoxy-1-(Methoxymethoxy)Benzene (CAS 195314-47-7)
- Semaglutide impurity 38 (CAS CATO-C4X-222638)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com