(4-chloro-7-fluoro-quinazolin-6-yl) acetate CAS 2743412-65-7
| CAS No. | 2743412-65-7 |
| Molecular Formula | C10H16ClFN2O2 |
| Molecular Weight | 250.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 250.70 g/mol gives (4-chloro-7-fluoro-quinazolin-6-yl) acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (4-chloro-7-fluoro-quinazolin-6-yl) acetate (CAS 2743412-65-7), a certified reference material (molecular formula C10H16ClFN2O2, MW 250.70 g/mol) for analytical method development and quality control.
(4-chloro-7-fluoro-quinazolin-6-yl) acetate (C10H16ClFN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (4-chloro-7-fluoro-quinazolin-6-yl) acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H16ClFN2O2 |
| Molecular Weight | 250.70 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- 3-Chloro-6-(4-fluorobenzyl)-4,5-dimethylpyridazine (CAS 1057682-70-8)
- 2-Chloro-N-(2-methoxyethyl)pyridine-3-sulfonamide (CAS 1155913-04-4)
- Methyl 4-chloro-2-((2-hydroxypropyl)amino)thiazole-5-carboxylate (CAS 1184498-64-3)
- 4-Chloro-2-(2-fluorophenyl)-6-isopropylpyrimidine (CAS 1239848-59-9)
- 5-Chloro-4-propoxypyridine-3-sulfonamide (CAS 1352506-61-6)
- 5-Chloro-N-ethyl-4-hydroxy-N-methylpyridine-3-sulfonamide (CAS 1352515-19-5)
- 5-Chloro-4-(isopropylamino)pyridine-3-sulfonic acid (CAS 1352516-05-2)
- 5-Chloro-4-(propylamino)pyridine-3-sulfonic acid (CAS 1352521-98-2)
Recommended Standards
- (4-Chloro-3-fluorophenyl)(p-tolyl)methanol (CAS 842140-55-0)
- 1-[4-(chloromethyl)phenoxymethyl]-4-fluorobenzene (CAS 613240-41-8)
- (4-Chloro-3-fluorophenyl)(m-tolyl)methanol (CAS 842140-71-0)
- 2-((2-Chlorothiazol-5-yl)methoxy)benzonitrile (CAS 860787-01-5)
- 2-(2,5-Difluorophenoxy)acetic acid (CAS 366-56-3)
- 4,4-Dimethyl-5'-phenyl-hexahydrospiro[cyclohexane-1,3'-pyrrolo[3,4-d][1,2]oxazole]-2,4',6,6'-tetrone (CAS 339011-75-5)
- 1-(1-Methoxycyclopropyl)-N-methylmethanamine (CAS 1638772-10-7)
- 3,3'-Bis(diphenylphosphanyl)-1,1'-binapthyl-2,2'-diyl hydrogenphosphate (CAS 1706439-25-9)
- 5-Aminopentan-2-one (CAS 3732-10-3)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarbaldehyde (CAS 151075-22-8)
- 2-Methyl-3-oxobutanal (CAS 22428-91-7)
- Eldecalcitol Impurity 35 (CAS 307953-25-9)
- 2-((3-(3-Bromophenyl)-1H-1,2,4-triazol-5-yl)thio)-N-(3-chlorophenyl)acetamide (CAS 332127-11-4)
- Tirzepatide Impurity 25 X TFA Salt (CAS CATO-C4X-324025)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com