Lubiprostone Impurity 30 CAS 2743427-14-5
| CAS No. | 2743427-14-5 |
| Molecular Formula | C20H32F2O5 |
| Molecular Weight | 390.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lubiprostone Impurity 30.
As a process- or degradation-related impurity, Lubiprostone Impurity 30 (CAS 2743427-14-5, C20H32F2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, a hydroxyl group, an ether linkage, fluorine substitution, Lubiprostone Impurity 30 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 390.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lubiprostone Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H32F2O5 |
| Molecular Weight | 390.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
Related Lubiprostone Standards
- Lubiprostone (CAS 136790-76-6/333963-40-9)
- Lubiprostone Impurity 18 (CAS 201226-21-3)
- Lubiprostone Impurity 3 (CAS 1263283-38-0)
- Lubiprostone Impurity 31 (CAS CATO-C4X-113631)
- Lubiprostone Impurity 32 (CAS CATO-C4X-113632)
- Lubiprostone Impurity 33 (CAS CATO-C4X-113633)
- Lubiprostone Impurity 35 (CAS 1808535-45-6 (Cyclo Form))
- Lubiprostone Impurity 40 (CAS CATO-C4X-113640)
Recommended Standards
- Sildenafil Impurity 76 (CAS CATO-C4X-112876)
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-5,6-dimethyl-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4-amine (CAS 796052-04-5)
- N-(5-Cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide (CAS 850935-88-5)
- Lubiprostone Impurity 41 (CAS CATO-C4X-113641)
- Dydrogesterone Impurity 23 (CAS CATO-C4X-218323)
- Nalmefene Impurity 27 (CAS CATO-C4X-126827)
- Ezetimibe Impurity 9 (CAS 163380-15-2)
- 4-Octenoic acid, methyl ester, (4Z)- (CAS 21063-71-8)
- 2-(3,4-Dimethoxyphenyl)-6-Fluoro-Benzothiazole (CAS 872726-53-9)
- 2-Morpholino-5-nitroaniline (CAS 4031-79-2)
- 4-(6-((3-Hydroxypropyl)amino)imidazo[1,2-b]pyridazin-3-yl)phenol (CAS 1012344-09-0)
- N-(o-tolyl)thietan-3-amine (CAS 1516574-59-6)
- Ethyl 1-(4-fluoro-5-methyl-2-nitrophenyl)piperidine-4-carboxylate hydrochloride (CAS 1261079-71-3)
- Hexapeptide-9 (CAS 885024-94-2)
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