Methyl 6-chloro-4-oxo-4h-chromene-2-carboxylate CAS 27455-31-8
| CAS No. | 27455-31-8 |
| Molecular Formula | C11H7ClO4 |
| Molecular Weight | 238.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 6-chloro-4-oxo-4h-chromene-2-carboxylate.
Methyl 6-chloro-4-oxo-4h-chromene-2-carboxylate (CAS 27455-31-8), molecular formula C11H7ClO4 and molecular weight 238.62 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 6-chloro-4-oxo-4h-chromene-2-carboxylate (C11H7ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7ClO4 |
| Molecular Weight | 238.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
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- Bis(2,2-bipyridyl)dichloro Osmium(II) (CAS 15702-72-4)
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- 2-Chloro-5-(morpholinosulfonyl)-1H-indole-3-carbaldehyde (CAS 535925-62-3)
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