3-(2-Chlorophenyl)-[1,2,4]triazolo[4,3-a]pyridine CAS 2746-41-0
| CAS No. | 2746-41-0 |
| Molecular Formula | C12H8ClN3 |
| Molecular Weight | 229.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Chlorophenyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 2746-41-0) is a high-purity analytical reference standard with the molecular formula C12H8ClN3 and a molecular weight of 229.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 3-(2-Chlorophenyl)-[1,2,4]triazolo[4,3-a]pyridine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 229.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8ClN3 |
| Molecular Weight | 229.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 2-((3-Chlorophenyl)amino)isonicotinonitrile (CAS 1019463-88-7)
- 6-(4-Chlorophenyl)imidazo[1,2-a]pyrimidine (CAS 1027511-33-6)
- 2-((2-Chlorophenyl)Amino)Nicotinonitrile (CAS 121005-01-4)
- 6-(3-Chlorophenyl)-2-methylpyrimidine-4-carbonitrile (CAS 1256638-56-8)
- 3-(4-Chlorophenyl)-3H-imidazo[4,5-b]pyridine (CAS 132458-91-4)
- 2-((3-Chlorophenyl)amino)nicotinonitrile (CAS 724745-64-6)
- 2-(4-Chlorophenyl)-[1,2,4]triazolo[1,5-a]pyridine (CAS 86848-88-6)
- 2-(4-Chlorophenyl)-1H-imidazo[4,5-c]pyridine (CAS 75007-94-2)
Recommended Standards
- 2-Chloro-4-phenyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 928840-88-4)
- 3-(4-Aminophenyl)-5-chloroisonicotinonitrile (CAS 886457-32-5)
- 2-Chloro-4-acetamido-6-(isopropylamino)-s-triazine (CAS 83364-15-2)
- 4-(Chloromethyl)-6-morpholin-4-yl-1,3,5-triazin-2-amine (CAS 21868-41-7)
- 2-Methyl-3-(6-methyl-2-pyridyl)-1-propene (CAS 951887-31-3)
- N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)hexanamide (CAS 63844-89-3)
- 1-[1-(4-bromo-2-methylphenyl)-1H-1,2,3-triazol-4-yl]-2,2,2-trifluoroethan-1-one (CAS 1461714-61-3)
- 7-Chloro-1H-pyrazolo[4,3-c]pyridin-3-amine (CAS 1956371-90-6)
- Nintedanib Impurity 5 (CAS 2036139-30-5)
- 3-(3-Chloro-2-methylphenyl)-1,1-dimethylthiourea (CAS 14501-92-9)
- Cycloartane (CAS 511-64-8)
- 2-Chloro-4-(1H-1,2,4-triazol-1-yl)benzohydrazide (CAS 952183-16-3)
- Pemafibrate Impurity 85 (CAS CATO-C4X-290385)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
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