Dimethyl (diazomethyl)phosphonate CAS 27491-70-9
| CAS No. | 27491-70-9 |
| Molecular Formula | C3H7N2O3P |
| Molecular Weight | 150.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dimethyl (diazomethyl)phosphonate is closely related to an amide group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dimethyl (diazomethyl)phosphonate (CAS 27491-70-9), molecular formula C3H7N2O3P and molecular weight 150.07 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Dimethyl (diazomethyl)phosphonate (C3H7N2O3P) is characterized by an amide group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H7N2O3P |
| Molecular Weight | 150.07 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.5 |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 2 |
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- Ethyl 4-(2-(3-amino-2-oxopyridin-1(2H)-yl)ethyl)morpholine-2-carboxylate (CAS 2171110-40-8)
- 3-methoxy-1-phenylpropan-1-one (CAS 55563-72-9)
- 1-(5-Methyl-1H-pyrazolo[3,4-c]pyridin-3-yl)ethan-1-one (CAS 1386457-36-8)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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