1,2,4,5-Tetrafluorobenzene CAS 327-54-8
| CAS No. | 327-54-8 |
| Molecular Formula | C6H2F4 |
| Molecular Weight | 150.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,2,4,5-Tetrafluorobenzene.
1,2,4,5-Tetrafluorobenzene (CAS 327-54-8), molecular formula C6H2F4 and molecular weight 150.07 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1,2,4,5-Tetrafluorobenzene (C6H2F4) contains fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 150.07 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,2,4,5-Tetrafluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H2F4 |
| Molecular Weight | 150.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Tetrafluorobenzene Standards
- 1,2,3,5-Tetrafluorobenzene (CAS 2367-82-0)
- 1,2,3,4-Tetrafluorobenzene (CAS 551-62-2)
- 2,3,5,6-Tetrafluorobenzene-1,4-diamine (CAS 1198-64-7)
- 3,4,5,6-Tetrafluorobenzene-1,2-diamine (CAS 2993-07-9)
- Tetrafluorobenzene-1,3-diol (CAS 16840-25-8)
- 3,4,5,6-Tetrafluorobenzene-1,2-diol (CAS 1996-23-2)
- 2,3,4,5-Tetrafluorobenzene-1-sulfonyl chloride (CAS 591249-21-7)
Recommended Standards
- 2,3-Difluoromaleamide (CAS 14703-27-6)
- Dimethyl (diazomethyl)phosphonate (CAS 27491-70-9)
- 3,3-Difluoro-2-oxopent-4-enoic acid (CAS 1535214-59-5)
- [3-(difluoromethyl)-1,2,4-oxadiazol-5-yl]methanol (CAS 1934455-03-4)
- (4-Fluorophenyl)trimethoxysilane (CAS 53883-61-7)
- 2-(Bromomethyl)-5-chloro-4-(difluoromethyl)-3-nitropyridine (CAS 1806895-18-0)
- 2-(5,6-Difluoro-4-(methoxymethoxy)naphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621935-28-0)
- 4-Amino-2-methoxy-5-(methylsulfonyl)benzoic Acid (CAS 71675-99-5)
- N-(6-(1-Ethoxyvinyl)pyridazin-3-yl)acetamide (CAS 1313712-40-1)
- (E)-1-(1H-Benzo[d][1,2,3]triazol-1-yl)-3-phenylprop-2-en-1-one (CAS 328012-09-5)
- 1-(4-Cyclopropylphenyl)propan-1-one (CAS 30170-62-8)
- 3-(3-chloro-2-methylphenyl)-2-sulfanyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one (CAS 380335-51-3)
- (3E,5E)-1-BENZYL-3,5-BIS(3-BROMO-4-HYDROXYBENZYLIDENE)PIPERIDIN-4-ONE 1020399-49-8 (CAS 1020399-49-8)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
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