4-(Difluoromethoxy)-6-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine CAS 2750605-73-1
| CAS No. | 2750605-73-1 |
| Molecular Formula | C12H17BF2N2O4 |
| Molecular Weight | 302.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Difluoromethoxy)-6-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine.
CATO supplies 4-(Difluoromethoxy)-6-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 2750605-73-1), a certified reference material (molecular formula C12H17BF2N2O4, MW 302.08 g/mol) for analytical method development and quality control.
Structurally, 4-(Difluoromethoxy)-6-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (C12H17BF2N2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.5, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 302.08 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(Difluoromethoxy)-6-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17BF2N2O4 |
| Molecular Weight | 302.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethoxy Standards
- 2-(2-(Difluoromethoxy)-6-fluoro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2913572-69-5)
- 3-(4-(Difluoromethoxy)phenyl)-1,1-dipropylthiourea (CAS 398995-99-8)
- N-(4-(Difluoromethoxy)phenyl)-2-methylquinazolin-4-amine (CAS 827031-10-7)
- 5-{[4-(difluoromethoxy)-3-methoxyphenyl]methylidene}-1,3-thiazolidine-2,4-dione (CAS 894259-20-2)
- 3-(Difluoromethoxy)-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 2201100-40-3)
- 4-(3-(4-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)aniline (CAS 1707609-07-1)
- 4-(3-(2-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)aniline (CAS 1708168-49-3)
- 3-(3-(4-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)aniline (CAS 1708250-78-5)
Recommended Standards
- (((5-Bromo-2-methylthiazol-4-yl)methoxy)methyl)phosphonic acid (CAS 261366-47-6)
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- Methyl 6-Iodoindazole-4-carboxylate (CAS 885519-74-4)
- 5-Bromo-2-(3-(trifluoromethyl)phenyl)pyridine (CAS 1215073-37-2)
- 2-Chloro-N-(pyridin-2-ylmethyl)acetamide (CAS 46120-62-1)
- 3-Methyl-1,2,4-thiadiazole-5-carboxamide (CAS 1448078-67-8)
- 3-Methylphenethyl acetate (CAS 33709-40-9)
- Tedizolid impurity 104 (CAS CATO-C4X-1054104)
- 7-(Chloromethyl)quinoline (CAS 97850-40-3)
- 6'-Bromo-4-methoxy-5''-methyl-3'H-dispiro[cyclohexane-1,2'-indene-1',2''-imidazol]-4''-amine (CAS 1383982-59-9)
- Dobutamine Impurity 51 (CAS CATO-C4X-129851)
- 1134333-99-5 4-(Hydroxymethyl)-5-methyl-1,2-oxazole-3-carboxylic acid DTXSID90673666 (CAS 1134333-99-5)
- (S)-2-((1R,3aS,7aR,E)-4-((E)-2-((S)-5-((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)propanal (CAS 112828-12-3)
- Exenatide (CAS 141758-74-9（free base）)
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