Ethinylestradiol EP Impurity E (6-alpha-Hydroxy Ethynylestradiol) CAS 27521-34-2
| CAS No. | 27521-34-2 |
| Molecular Formula | C20H24O3 |
| Molecular Weight | 312.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ethinylestradiol EP Impurity E (6-alpha-Hydroxy Ethynylestradiol) (CAS 27521-34-2, C20H24O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H24O3, Ethinylestradiol EP Impurity E (6-alpha-Hydroxy Ethynylestradiol) contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 312.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ethinylestradiol EP Impurity E (6-alpha-Hydroxy Ethynylestradiol) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H24O3 |
| Molecular Weight | 312.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
Related Ethinylestradiol Standards
- Ethinylestradiol EP Impurity F (CAS 56324-28-8)
- Ethinylestradiol 2-Hydroxy Impurity (CAS 50394-89-3)
- Ethinylestradiol 1-Hydroxy 4-Methyl Impurity (CAS 1034298-00-4)
- Ethinylestradiol EP Impurity J (CAS 15071-66-6)
- Ethinylestradiol EP Impurity K (CAS 155683-61-7)
- Ethinylestradiol EP Impurity M (CAS 3240-39-9)
- Ethinylestradiol EP Impurity G (CAS 38002-18-5)
- Ethinylestradiol EP Impurity H (CAS 1350468-76-6)
Recommended Standards
- Denaverine Impurity 1 (CAS 2594-45-8)
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- Roxithromycin Impurity 20 (CAS 1460313-65-8)
- Montelukast Impurity 44 (CAS 2365398-66-7)
- Dibutylstannanediyl bis(2-ethylhexanoate) (CAS 2781-10-4)
- 1-Tosyl-1H-indole-2-carbaldehyde (CAS 146384-54-5)
- Tolterodine Impurity N5 (CAS 1189501-90-3)
- 38945-21-0 EBD2204383 O-1-allylhydroxylamine hydrochloride; O-prop-2-enylhydroxylamine hydrochloride (CAS 38945-21-0)
- Homovanillic Acid-d3 (CAS 74495-71-9)
- 3-Iodo-7-methyl-1H-indole (CAS 1360934-48-0)
- Semaglutide impurity 28 (CAS CATO-C4X-222628)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com