Ethinylestradiol 2-Hydroxy Impurity CAS 50394-89-3
| CAS No. | 50394-89-3 |
| Molecular Formula | C20H24O3 |
| Molecular Weight | 312.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethinylestradiol 2-Hydroxy Impurity (C20H24O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Ethinylestradiol 2-Hydroxy Impurity (CAS 50394-89-3) is a certified pharmaceutical impurity reference standard with the molecular formula C20H24O3 and a molecular weight of 312.40 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ethinylestradiol 2-Hydroxy Impurity under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H24O3 |
| Molecular Weight | 312.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
Related Ethinylestradiol Standards
- Ethinylestradiol EP Impurity F (CAS 56324-28-8)
- Ethinylestradiol EP Impurity E (6-alpha-Hydroxy Ethynylestradiol) (CAS 27521-34-2)
- Ethinylestradiol 1-Hydroxy 4-Methyl Impurity (CAS 1034298-00-4)
- Ethinylestradiol EP Impurity J (CAS 15071-66-6)
- Ethinylestradiol EP Impurity K (CAS 155683-61-7)
- Ethinylestradiol EP Impurity M (CAS 3240-39-9)
- Ethinylestradiol EP Impurity G (CAS 38002-18-5)
- Ethinylestradiol EP Impurity H (CAS 1350468-76-6)
Recommended Standards
- Epoxy Exemestane (6 Alpha , Beta Isomer) (CAS 184972-12-1)
- Estriol EP Impurity K (CAS 901-93-9)
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- 4,4-Difluoro-2-methoxy-2-methylcyclohexan-1-one (CAS 2839564-85-9)
- Zanamivir Hydrate (CAS 1260601-68-0)
- Insulin Detemir (CAS 169148-63-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com