5-(Trifluoromethyl)spiro[indoline-2,4'-piperidin]-3-one CAS 2752430-60-5
| CAS No. | 2752430-60-5 |
| Molecular Formula | C13H13F3N2O |
| Molecular Weight | 270.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(Trifluoromethyl)spiro[indoline-2,4'-piperidin]-3-one (CAS 2752430-60-5) is a high-purity analytical reference standard with the molecular formula C13H13F3N2O and a molecular weight of 270.25 g/mol.
Based on its molecular formula C13H13F3N2O, 5-(Trifluoromethyl)spiro[indoline-2,4'-piperidin]-3-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 270.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H13F3N2O |
| Molecular Weight | 270.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 3-(trifluoromethyl)-7,8,9,10-tetrahydro-5H-pyrido[1,2-a]quinoxalin-6(6aH)-one (CAS 1009240-54-3)
- 2-(Trifluoromethyl)-2’,3’,4’,5’-tetrahydrobiphenyl-4-carboxylic Acid (CAS 1034188-31-2)
- 1-(Trifluoromethyl)pyrene (CAS 1186194-78-4)
- 1-(4-(Trifluoromethyl)phenyl)bicyclo[2.1.1]Hexane-5-carboxylic acid (CAS 2219380-08-0)
- 2-[3-(trifluoromethyl)benzoyl]cyclohexan-1-one (CAS 444077-10-5)
- 3-[6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]piperidine (CAS 901273-41-4)
- 6-(Trifluoromethyl)-2H-spiro[benzofuran-3,1'-cyclohexan]-4'-one (CAS 2351201-09-5)
- Methyl 3-(4-(trifluoromethyl)phenyl)bicyclo[1.1.1]Pentane-1-carboxylate (CAS 2074610-52-7)
Recommended Standards
- 5-(2,4-Difluorophenoxymethyl)thiophene-2-carboxylic acid (CAS 934127-23-8)
- 4,4'-Oxydiphthalonitrile (CAS 23277-29-4)
- 9-(3-Nitrobenzyl)-9H-purin-6-amine (CAS 7008-55-1)
- 3-benzyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide (CAS 85623-02-5)
- 2-((3-Chlorobenzyl)oxy)-6-(piperazin-1-yl)pyrazine hydrochloride (CAS 1215721-40-6)
- 3-{5-[(2E)-3-(4-chlorophenyl)prop-2-enoyl]-4-methyl-1,3-thiazol-2-yl}-1-methylpyridin-1-ium iodide (CAS 477712-99-5)
- Ethyl 2-(5-Nitropyridin-2-yl)acetate (CAS 174890-57-4)
- (1s,2s)-2-(Pyridin-3-yl)cyclopropane-1-carboxylic acid (CAS 1620644-49-6)
- 4-Phenyl-2-(pyridin-3-yl)thiazole-5-carboxylic acid (CAS 51492-89-8)
- Ethyl 4,5-Dimethylthiophene-3-carboxylate (CAS 19156-44-6)
- 3-Acetamido-6-(acetoxymethyl)tetrahydro-2H-pyran-2,4,5-triyl triacetate (CAS 582318-96-5)
- 1-Methyl-1H-imidazole-2-carbothioamide (CAS 885281-13-0)
- Atropine Impurity 35 (CAS 5928-44-9)
- Liraglutide (CAS 204656-20-2)
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