5-(2,4-Difluorophenoxymethyl)thiophene-2-carboxylic acid CAS 934127-23-8
| CAS No. | 934127-23-8 |
| Molecular Formula | C12H8F2O3S |
| Molecular Weight | 270.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 270.25 g/mol gives 5-(2,4-Difluorophenoxymethyl)thiophene-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(2,4-Difluorophenoxymethyl)thiophene-2-carboxylic acid (CAS 934127-23-8) is a high-purity analytical reference standard with the molecular formula C12H8F2O3S and a molecular weight of 270.25 g/mol.
Structurally, 5-(2,4-Difluorophenoxymethyl)thiophene-2-carboxylic acid (C12H8F2O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 270.25 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8F2O3S |
| Molecular Weight | 270.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluorophenoxymethyl Standards
- 5-(2,4-difluorophenoxymethyl)-1,2-oxazole-3-carboxylic acid (CAS 932917-90-3)
- 5-(2,4-Difluorophenoxymethyl)furan-2-carboxylic acid (CAS 832740-42-8)
- 5-(2,4-Difluorophenoxymethyl)furan-2-carbaldehyde (CAS 438222-04-9)
- 2-(3,4-Difluorophenoxymethyl)morpholine (CAS 1171773-00-4)
- 3-(3,4-Difluorophenoxymethyl)azetidine (CAS 954226-20-1)
Recommended Standards
- 4,4'-Oxydiphthalonitrile (CAS 23277-29-4)
- 5-(Trifluoromethyl)spiro[indoline-2,4'-piperidin]-3-one (CAS 2752430-60-5)
- 3-benzyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide (CAS 85623-02-5)
- 6-(Trifluoromethyl)-2H-spiro[benzofuran-3,1'-cyclohexan]-4'-one (CAS 2351201-09-5)
- Ethyl 2-(difluoromethyl)-8-methylimidazo[1,2-a]pyridine-3-carboxylate (CAS 2514942-05-1)
- 86520-54-9 1-O-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)-2-acetamido-2deoxy-beta-D-glucopyranoside MFCD21363174 (CAS 86520-54-9)
- N-(2-Bromophenyl)-2-(pyridin-2-ylsulfanyl)acetamide (CAS 329078-68-4)
- 2-Cyclopropoxy-3-fluorobenzaldehyde (CAS 1243399-18-9)
- Ethyl 3-(Trifluoromethyl)pyrazole-5-carboxylate (CAS 129768-30-5)
- N-Phenyl-2-{[3-(trifluoromethyl)quinoxalin-2-yl]sulfanyl}acetamide (CAS 321433-75-4)
- Potassium 3-fluoropyridine-4-trifluoroborate (CAS 1451390-70-7)
- n-(Pyridin-3-ylmethyl)benzenesulfonamide (CAS 244050-23-5)
- 4-Ethoxy-3-methylpicolinonitrile (CAS 30235-24-6)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
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