3-(4-Bromo-2,6-difluorophenyl)piperidine-2,6-dione CAS 2758533-77-4

Purity 97%+In StockPharmaceutical Standards
CAS No.2758533-77-4
Molecular FormulaC11H8BrF2NO2
Molecular Weight304.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Bromo-2,6-difluorophenyl)piperidine-2,6-dione CAS 2758533-77-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

3-(4-Bromo-2,6-difluorophenyl)piperidine-2,6-dione (CAS 2758533-77-4) is a high-purity analytical reference standard with the molecular formula C11H8BrF2NO2 and a molecular weight of 304.09 g/mol.

3-(4-Bromo-2,6-difluorophenyl)piperidine-2,6-dione (C11H8BrF2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), 3-(4-Bromo-2,6-difluorophenyl)piperidine-2,6-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H8BrF2NO2
Molecular Weight304.09 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Halogen ContentF/Br-containing
Nitrogen Atoms1

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