[(2R,3R,4R,5R)-5-bromo-3-tert-butoxycarbonyloxy-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl tert-butyl carbonate CAS 2761681-33-6
| CAS No. | 2761681-33-6 |
| Molecular Formula | C16H26BrFO7 |
| Molecular Weight | 429.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [(2R,3R,4R,5R)-5-bromo-3-tert-butoxycarbonyloxy-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl tert-butyl carbonate.
[(2R,3R,4R,5R)-5-bromo-3-tert-butoxycarbonyloxy-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl tert-butyl carbonate (CAS 2761681-33-6), molecular formula C16H26BrFO7 and molecular weight 429.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of [(2R,3R,4R,5R)-5-bromo-3-tert-butoxycarbonyloxy-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl tert-butyl carbonate (C16H26BrFO7) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H26BrFO7 |
| Molecular Weight | 429.28 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Br-containing |
Recommended Standards
- Dotinurad Impurity 70 (CAS CATO-C4X-249470)
- 2-(2-(2,4-Dichlorophenoxy)propanoyl)-N-(4-nitrophenyl)hydrazine-1-carbothioamide (CAS 894574-75-5)
- Methyl (E)-2-((4-((((2,6-dichlorobenzyl)oxy)imino)methyl)-2-nitrophenyl)thio)acetate (CAS 477858-97-2)
- 4-(((4AR,6R,7R,7aR)-6-(6-amino-9H-purin-9-yl)-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl)oxy)-4-oxobutanoic acid (CAS 36940-87-1)
- 2-Chloro-5-((piperidin-3-yloxy)methyl)pyridine dihydrochloride (CAS 1185309-77-6)
- 4-(Cyclopropylamino)butan-2-one (CAS 155562-24-6)
- (3-Fluoro-5-methylthiophen-2-yl)(4-methoxyphenyl)methanol (CAS 1285067-83-5)
- N-((1-(3,4-Difluorophenyl)-1H-tetrazol-5-yl)methyl)-3-methylbutanamide (CAS 941922-06-1)
- 4-Nitro-5-phenyl-2H-1,2,3-triazole (CAS 56745-99-4)
- 3,5-Dimethyl-1-(2-(methylsulfonyl)ethyl)-1h-pyrazol-4-amine (CAS 1183447-41-7)
- Olmesartan Impurity 111 (CAS 1073117-27-7)
- 4'-Chloro-3-methyl-[1,1'-biphenyl]-4-ol (CAS 1261916-91-9)
- 1,4-Di(1,3-dioxan-2-yl)butane (CAS 111865-42-0)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com