Olmesartan Impurity 111 CAS 1073117-27-7

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.1073117-27-7
Molecular FormulaC45H38N6O6
Molecular Weight758.82 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Olmesartan Impurity 111 CAS 1073117-27-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 758.82 g/mol gives Olmesartan Impurity 111 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Olmesartan Impurity 111 (CAS 1073117-27-7) is a certified pharmaceutical impurity reference standard with the molecular formula C45H38N6O6 and a molecular weight of 758.82 g/mol.

The molecular framework of Olmesartan Impurity 111 (C45H38N6O6) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Olmesartan Impurity 111 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC45H38N6O6
Molecular Weight758.82 g/mol
Purity≥95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)30.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Nitrogen Atoms6

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