methyl 2,2-difluoro-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate CAS 2763679-34-9
| CAS No. | 2763679-34-9 |
| Molecular Formula | C11H16F2O4 |
| Molecular Weight | 250.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including methyl 2,2-difluoro-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate.
CATO supplies methyl 2,2-difluoro-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate (CAS 2763679-34-9), a certified reference material (molecular formula C11H16F2O4, MW 250.24 g/mol) for analytical method development and quality control.
methyl 2,2-difluoro-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate (C11H16F2O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), methyl 2,2-difluoro-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16F2O4 |
| Molecular Weight | 250.24 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
Related methyl Standards
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- 3,3'-Difluoro-4,4'-dimethoxy-1,1'-biphenyl (CAS 41860-57-5)
- Ethyl 2,2-Difluoro-2-(1-naphthyl)acetate (CAS 73790-00-8)
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Recommended Standards
- Ethyl 4-((trifluoromethyl)thio)benzoate (CAS 587-19-9)
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- Elagolix Impurity 4 (CAS 2316733-82-9)
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- N-Boc-3-aminophenylacetic Acid (CAS 123036-51-1)
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- N-(3,4-Dichlorobenzyl)-3-nitropyridin-2-amine (CAS 866154-67-8)
- 2-ethynyl-6-azaspiro[2.5]octane;hydrochloride (CAS 2098119-61-8)
- tert-Butyl 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-azaspiro[3.5]non-6-ene-2-carboxylate (CAS 2351276-13-4)
- 5-Chloro-2-pyridylacetonitrile (CAS 185315-51-9)
- Perfluorotriethylamine (CAS 359-70-6)
- 6,6-dimethoxy-2,2-dimethylhexan-1-amine (CAS 1803610-20-9)
- Peptide 440 (CAS CATO-CPTD788440)
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