N-Boc-4,4-difluoro-L-prolinamide CAS 426844-50-0
| CAS No. | 426844-50-0 |
| Molecular Formula | C10H16F2N2O3 |
| Molecular Weight | 250.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures N-Boc-4,4-difluoro-L-prolinamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies N-Boc-4,4-difluoro-L-prolinamide (CAS 426844-50-0), a certified reference material (molecular formula C10H16F2N2O3, MW 250.24 g/mol) for analytical method development and quality control.
N-Boc-4,4-difluoro-L-prolinamide (C10H16F2N2O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H16F2N2O3 |
| Molecular Weight | 250.24 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- methyl 2,2-difluoro-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate (CAS 2763679-34-9)
- tert-Butyl (3aS,6aS)-6,6-difluorohexahydro-4H-pyrrolo[3,2-c]isoxazole-4-carboxylate (CAS 2597336-75-7)
- Ethyl 4-((trifluoromethyl)thio)benzoate (CAS 587-19-9)
- Elagolix Impurity 4 (CAS 2316733-82-9)
- 4-(2-Methoxyethyl)pyridine (CAS 70289-28-0)
- Ethyl 3,4-difluoro-2-methoxyphenylacetate (CAS 1806330-92-6)
- 2-chloro-N-(2-methylpropyl)-N-(propan-2-yl)acetamide (CAS 39096-40-7)
- n-((5-Sulfamoylthiophen-2-yl)methyl)propionamide (CAS 1099052-73-9)
- Roflumilast Impurity 4 (CAS 162401-30-1)
- Cefiderocol (CAS 1225208-94-5)
- L-Citrulline D2 (CAS 1021439-17-7)
- 895010-58-9 4-(2-Methoxyphenyl)-5-methyl-1H-pyrazol-3-amine DTXSID50586485 (CAS 895010-58-9)
- 2-Amino-4-((trifluoromethyl)sulfinyl)phenol (CAS 1616682-59-7)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com