2-[(4-chloro-6-methyl-pyrazolo[3,4-d]pyrimidin-1-yl)methoxy]ethyl-trimethyl-silane CAS 2765271-80-3

Description

The occurrence of 2-[(4-chloro-6-methyl-pyrazolo[3,4-d]pyrimidin-1-yl)methoxy]ethyl-trimethyl-silane is closely related to an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-[(4-chloro-6-methyl-pyrazolo[3,4-d]pyrimidin-1-yl)methoxy]ethyl-trimethyl-silane (CAS 2765271-80-3), a certified reference material (molecular formula C12H27ClN4OSi, MW 306.91 g/mol) for analytical method development and quality control.

The molecular framework of 2-[(4-chloro-6-methyl-pyrazolo[3,4-d]pyrimidin-1-yl)methoxy]ethyl-trimethyl-silane (C12H27ClN4OSi) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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