tert-Butyl 3-(3-bromo-2,2-difluoropropanoyl)azetidine-1-carboxylate CAS 2766367-08-0
| CAS No. | 2766367-08-0 |
| Molecular Formula | C11H16BrF2NO3 |
| Molecular Weight | 328.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of tert-Butyl 3-(3-bromo-2,2-difluoropropanoyl)azetidine-1-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
tert-Butyl 3-(3-bromo-2,2-difluoropropanoyl)azetidine-1-carboxylate (CAS 2766367-08-0) is a high-purity analytical reference standard with the molecular formula C11H16BrF2NO3 and a molecular weight of 328.15 g/mol.
tert-Butyl 3-(3-bromo-2,2-difluoropropanoyl)azetidine-1-carboxylate (C11H16BrF2NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), tert-Butyl 3-(3-bromo-2,2-difluoropropanoyl)azetidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16BrF2NO3 |
| Molecular Weight | 328.15 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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- Rimegepant Impurity 72 (CAS CATO-C4X-248772)
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