Upadacitinib Impurity 10 CAS 2768445-17-4
| CAS No. | 2768445-17-4 |
| Molecular Formula | C34H39N5O7S |
| Molecular Weight | 661.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Upadacitinib Impurity 10.
Upadacitinib Impurity 10 (CAS 2768445-17-4) is a certified pharmaceutical impurity reference standard with the molecular formula C34H39N5O7S and a molecular weight of 661.77 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Upadacitinib Impurity 10 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 661.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Upadacitinib Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C34H39N5O7S |
| Molecular Weight | 661.77 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 117 (CAS CATO-C4X-2405117)
- Upadacitinib Impurity 14 (CAS 1428243-27-9)
- Upadacitinib Impurity 90 (CAS CATO-C4X-240590)
- Upadacitinib Impurity 32 (CAS 2715120-88-8)
- Upadacitinib Impurity 25 (CAS 2050038-81-6)
- Upadacitinib Impurity 39 (CAS 2715120-95-7)
- Upadacitinib Impurity 40 (CAS CATO-C4X-240540)
- Upadacitinib Impurity 82 (CAS CATO-C4X-240582)
Recommended Standards
- 2,7-Bis(alloxycarbonylamino)-9-(biotinylaminoethylamino)acridine (CAS 1219125-65-1)
- Fmoc-β-Ala-Lys(Fmoc)-OH (CAS CATO-CPTD788973)
- 10-Hydroxy Aconitine (CAS 41849-35-8)
- Famotidine Impurity 77 (CAS CATO-C4X-139277)
- Beraprost Impurity 7 (CAS CATO-C4X-21847)
- Betahistine Impurity 18 (CAS 24028-46-4)
- Menaquinone impurity 22 (CAS CATO-C4X-207622)
- Naphthol AS-BI N-acetyl-b-D-galactosaminide (CAS 59985-23-8)
- 1,3,6,8-Tetrahydroxyanthracene-9,10-dione (CAS 52940-12-2)
- 2,3,6-Trifluorobenzenesulfonyl chloride (CAS 1017779-75-7)
- 2-Hydroxy-4-(((2-thioxobenzo[d]oxazol-3(2H)-yl)methyl)amino)benzoic acid (CAS 56617-09-5)
- 5-(2-Methoxybenzylidene)thiazolidine-2,4-dione (CAS 5835-46-1)
- 1-(2,4-Dimethylphenyl)-2,5-dimethyl-1h-pyrrole-3-carbaldehyde (CAS 328028-87-1)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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