Upadacitinib Impurity 213 CAS 2768445-19-6
| CAS No. | 2768445-19-6 |
| Molecular Formula | C23H22F3N5O3S |
| Molecular Weight | 505.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C23H22F3N5O3S, Upadacitinib Impurity 213 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 505.51 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Upadacitinib Impurity 213 (CAS 2768445-19-6) is a certified pharmaceutical impurity reference standard with the molecular formula C23H22F3N5O3S and a molecular weight of 505.51 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H22F3N5O3S |
| Molecular Weight | 505.51 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 168 (CAS CATO-C4X-2405168)
- Upadacitinib Impurity 193 (CAS CATO-C4X-2405193)
- Upadacitinib Impurity 21 (CAS 2715120-86-6)
- Upadacitinib Impurity 130 (CAS CATO-C4X-2405130)
- Upadacitinib Impurity 131 (CAS CATO-C4X-2405131)
- Upadacitinib Impurity 135 (CAS CATO-C4X-2405135)
- Upadacitinib Impurity 5 (CAS CATO-C4X-24055)
- Upadacitinib Impurity 210 (CAS CATO-C4X-2405210)
Recommended Standards
- (5|A)-4,5-Epoxy-6,14-dihydroxy-17-(2-propenyl)morphinan-3-yl |A-D-Glucopyranosiduronic Acid 24326-39-4 Naloxol 3-|A-D-Glucuronide Naloxol-3-glucuronide (CAS 24326-39-4)
- Ampkinone (CAS 1233082-79-5)
- 3-[[5-[2,2-dimethyl-4-(oxetan-3-yl)piperazin-1-yl]-2-pyridyl]amino]-1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-one (CAS 2696453-81-1)
- ((2R,3S,5S)-3-((4-Methylbenzoyl)oxy)-5-(7-oxo-3,4-dihydro-1H-pyrimido[4,5-c][1,2]oxazin-6(7H)-yl)tetrahydrofuran-2-yl)methyl 4-methylbenzoate (CAS 126128-41-4)
- Promethazine Impurity 56 (CAS CATO-C4X-141856)
- Nerandomilast impurity 3 (CAS CATO-C4X-34733)
- Tadalafil Impurity 75 (CAS 1093940-68-1)
- Bosutinib 4-Hydroxy 7-Chloropropoxy Impurity (CAS 214470-66-3)
- Boric anhydride (CAS 1303-86-2)
- 6-Chloro-9-ethyl-9H-purin-2-amine (CAS 130584-29-1)
- Norglaucine (CAS 21848-62-4)
- 2-Chloro-N-((5-(furan-2-yl(hydroxy)methyl)thiophen-2-yl)methyl)benzamide (CAS 1795303-06-8)
- 2,3-Difluoro-N-methyl-6-nitroaniline (CAS 170432-54-9)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
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