1,4-Bis(difluoromethoxy)benzene CAS 27691-15-2
| CAS No. | 27691-15-2 |
| Molecular Formula | C8H6F4O2 |
| Molecular Weight | 210.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 210.13 g/mol gives 1,4-Bis(difluoromethoxy)benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1,4-Bis(difluoromethoxy)benzene (CAS 27691-15-2), a certified reference material (molecular formula C8H6F4O2, MW 210.13 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 1,4-Bis(difluoromethoxy)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 210.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1,4-Bis(difluoromethoxy)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F4O2 |
| Molecular Weight | 210.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
Related Bis Standards
- 1,2-Bis(difluoromethoxy)benzene (CAS 27691-14-1)
- 1,3-Bis(difluoromethoxy)benzene (CAS 22236-12-0)
- 5-(Difluoromethoxy)-4-fluoro-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1779129-04-2)
- 8-(difluoromethoxy)quinolin-5-amine (CAS 1082893-09-1)
- 2-(Difluoromethoxy)-7-naphthol (CAS 1094284-18-0)
- 1-(Difluoromethoxy)-3-naphthol (CAS 1261600-48-9)
- 2-(Difluoromethoxy)-6-naphthol (CAS 1261600-56-9)
- 2-(Difluoromethoxy)-5-naphthol (CAS 1261787-71-6)
Recommended Standards
- 1,4-Dimethoxytetrafluorobenzene (CAS 362-56-1)
- 1-Ethyl-5-fluoro-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 479638-63-6)
- (S)-2-Amino-4-(ethylselanyl)butanoic acid (CAS 20999-05-7)
- 2-(1,1,2,2-tetrafluoroethoxy)phenol (CAS 88553-88-2)
- 1-(3-Chloro-4-methylphenyl)pyrrolidin-3-amine (CAS 1181309-51-2)
- N-(2-Bromophenyl)-N’-(1,2-diphenylethylidene)hydrazine (CAS 945242-95-5)
- 20-Hydroxyecdysone (CAS 5289-74-7)
- 3-(4-Acetylphenyl)acrylic acid ethyl ester, 97% (CAS 82989-26-2)
- 1-(4-Methoxybenzyl)-1H-pyrazole-5-carbaldehyde (CAS 162468-77-1)
- (2S,3R)-1-Cbz-2-methyl-piperidine-3-carboxylic acid (CAS 1260617-68-2)
- 2-(Benzyloxy)-3-methylbenzaldehyde (CAS 52803-61-9)
- N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-5-yl)acetamide (CAS 50698-85-6)
- Tadalafil Impurity 17 (CAS 629652-42-2)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
Why CATO?
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