Nintedanib Impurity 84 CAS 2770008-35-8
| CAS No. | 2770008-35-8 |
| Molecular Formula | C14H13NO5 |
| Molecular Weight | 275.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nintedanib Impurity 84.
Nintedanib Impurity 84 (CAS 2770008-35-8) is a certified pharmaceutical impurity reference standard with the molecular formula C14H13NO5 and a molecular weight of 275.26 g/mol.
Nintedanib Impurity 84 (C14H13NO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity 84 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H13NO5 |
| Molecular Weight | 275.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 1 |
Related Nintedanib Standards
- Nintedanib Impurity 93 (CAS CATO-C4X-181493)
- Nintedanib Impurity 132 (CAS CATO-C4X-1814132)
- Nintedanib Impurity 169 (CAS CATO-C4X-1814169)
- Nintedanib Impurity 185 (CAS 652140-07-3)
- Nintedanib Impurity 95 (CAS 16320-52-8)
- Nintedanib Impurity 127 (CAS CATO-C4X-1814127)
- Nintedanib Impurity 9 (CAS 1038972-16-5)
- Nintedanib Impurity 102 (CAS CATO-C4X-1814102)
Recommended Standards
- Metronidazole Impurity 9 (CAS 87009-72-1)
- Phenyl (4,6-Dimethoxy-2-pyrimidinyl)carbamate (CAS 89392-03-0)
- Lenalidomide Impurity 56 (CAS 1421593-78-3)
- 3-Nitrobenzanthrone (CAS 17117-34-9)
- FCN437 Impurity 5 (CAS CATO-C4X-33245)
- Peramivir Impurity 20 (CAS CATO-C4X-183320)
- Trazodone Impurity 43 (CAS CATO-C4X-177243)
- Canagliflozin Impurity 104 (CAS CATO-C4X-1123104)
- 1-Isopropyl-3-(thiophen-2-yl)urea (CAS 903151-28-0)
- 1-(2-((2-Methoxyethyl)amino)-2-oxoethyl)-1H-pyrrole-3-carboxylic acid (CAS 1510251-69-0)
- 4-((4-(Tert-butyl)phenyl)amino)-4-oxobutanoic acid (CAS 329079-35-8)
- 3-(4-Aminophenoxy)benzamide (CAS 284462-85-7)
- 2-(((2-Bromopyridin-4-yl)methyl)(isopropyl)amino)acetic acid (CAS 1353962-22-7)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com