tert-Butyl 3-iodo-5-methyl-6,7-dihydropyrazolo[1,5-a]pyrimidine-4(5H)-carboxylate CAS 2770271-24-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2770271-24-2
Molecular FormulaC12H18IN3O2
Molecular Weight363.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl 3-iodo-5-methyl-6,7-dihydropyrazolo[1,5-a]pyrimidine-4(5H)-carboxylate CAS 2770271-24-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl 3-iodo-5-methyl-6,7-dihydropyrazolo[1,5-a]pyrimidine-4(5H)-carboxylate.

tert-Butyl 3-iodo-5-methyl-6,7-dihydropyrazolo[1,5-a]pyrimidine-4(5H)-carboxylate (CAS 2770271-24-2), molecular formula C12H18IN3O2 and molecular weight 363.19 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of tert-Butyl 3-iodo-5-methyl-6,7-dihydropyrazolo[1,5-a]pyrimidine-4(5H)-carboxylate (C12H18IN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl 3-iodo-5-methyl-6,7-dihydropyrazolo[1,5-a]pyrimidine-4(5H)-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H18IN3O2
Molecular Weight363.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Halogen ContentI-containing
Nitrogen Atoms3

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