2-(2,6-dioxo-3-piperidyl)-5-[2-hydroxyethyl(methyl)amino]isoindoline-1,3-dione CAS 2770573-06-1
| CAS No. | 2770573-06-1 |
| Molecular Formula | C16H17N3O5 |
| Molecular Weight | 331.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(2,6-dioxo-3-piperidyl)-5-[2-hydroxyethyl(methyl)amino]isoindoline-1,3-dione (CAS 2770573-06-1), molecular formula C16H17N3O5 and molecular weight 331.32 g/mol, is a CATO reference standard with documented purity and traceability.
2-(2,6-dioxo-3-piperidyl)-5-[2-hydroxyethyl(methyl)amino]isoindoline-1,3-dione (C16H17N3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-(2,6-dioxo-3-piperidyl)-5-[2-hydroxyethyl(methyl)amino]isoindoline-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H17N3O5 |
| Molecular Weight | 331.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 3 |
Related dioxo Standards
- 14-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxatetradecanoic acid (CAS 1286754-10-6)
- 2-(2,6-dioxo-3-piperidyl)-4-(2-methoxyethylamino)isoindoline-1,3-dione (CAS 444287-93-8)
- 2-(2,6-dioxo-3-piperidyl)-4-(3-hydroxypropylamino)isoindoline-1,3-dione (CAS 2289788-04-9)
- 2-(2,6-dioxo-3-piperidyl)-5-(3-hydroxypropylamino)isoindoline-1,3-dione (CAS 2736496-63-0)
- 2-(2,6-dioxo-3-piperidyl)-5-[2-(methylamino)ethoxy]isoindoline-1,3-dione (CAS 2243885-39-2)
- 3-[[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]amino]propanoic acid (CAS 2338824-28-3)
- Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-inden-2-yliden)methyl]-1H-indole-2-carboxylate (CAS 860611-90-1)
- N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]-2-methoxy-acetamide (CAS 2321264-58-6)
Recommended Standards
- 2-(4-Nitrophenoxy)-N-[2-(4-nitrophenyl)-ethyl]ethanamine (CAS 226992-13-8)
- 2-(5-Cyano-6-oxo-3,4-diphenylpyridazin-1(6H)-yl)acetic acid (CAS 82232-21-1)
- 3'-Amino-6'-hydroxy-3h-spiro[2-benzofuran-1,9'-xanthen]-3-one (CAS 3086-44-0)
- 1-(Bromomethyl)-4-(phenylsulfonyl)benzene (CAS 7705-63-7)
- (4-Nitro-3-(trifluoromethyl)phenyl)methanol (CAS 936234-83-2)
- 5-Bromo-4,6-dichloro-2-methoxypyrimidine (CAS 1240596-72-8)
- 3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]propan-1-amine hydrochloride (CAS 1909319-53-4)
- Methyl 6-ethynylpicolinate (CAS 914950-66-6)
- 3-Ethyl-2-(2-methoxyphenyl)-5-(phenylamino)-2H-indazole-4,7-dione (CAS 62370-36-9)
- 6-(4-Methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine (CAS 1628502-91-9)
- Methyl 4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 61707-79-7)
- Methyl 5-chloropicolinate hydrochloride (CAS 1956318-06-1)
- (S)-2-Amino-3-(4-fluoro-3-hydroxyphenyl)propanoic acid hydrochloride (CAS 132732-79-7)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
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