(E)-3-(furan-2-yl)-2-(4-phenylthiazol-2-yl)acrylonitrile CAS 277308-31-3

Purity 97%+In StockPharmaceutical Standards
CAS No.277308-31-3
Molecular FormulaC16H10N2OS
Molecular Weight278.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-3-(furan-2-yl)-2-(4-phenylthiazol-2-yl)acrylonitrile CAS 277308-31-3 chemical structure

Description

(E)-3-(furan-2-yl)-2-(4-phenylthiazol-2-yl)acrylonitrile (C16H10N2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

(E)-3-(furan-2-yl)-2-(4-phenylthiazol-2-yl)acrylonitrile (CAS 277308-31-3) is a high-purity analytical reference standard with the molecular formula C16H10N2OS and a molecular weight of 278.33 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H10N2OS
Molecular Weight278.33 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2
Sulfur Atoms1

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