1-(Trifluoromethyl)cyclobutanecarboxylic Acid CAS 277756-45-3
| CAS No. | 277756-45-3 |
| Molecular Formula | C6H7F3O2 |
| Molecular Weight | 168.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(Trifluoromethyl)cyclobutanecarboxylic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(Trifluoromethyl)cyclobutanecarboxylic Acid (CAS 277756-45-3), molecular formula C6H7F3O2 and molecular weight 168.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(Trifluoromethyl)cyclobutanecarboxylic Acid (C6H7F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(Trifluoromethyl)cyclobutanecarboxylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H7F3O2 |
| Molecular Weight | 168.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1093750-93-6)
- cis-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 123812-82-8)
- trans-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 123812-83-9)
- 2-[1-(Trifluoromethyl)cyclopropyl]acetic Acid (CAS 1368342-07-7)
- 2-(trifluoromethyl)furan-3-carbaldehyde (CAS 1378259-70-1)
- 5-(trifluoromethyl)furan-2-carbaldehyde (CAS 17515-80-9)
- 2-(Trifluoromethyl)dihydro-2H-pyran-4(3H)-one (CAS 1803611-31-5)
- 2-(Trifluoromethyl)cyclobutane-1-carboxylic acid (CAS 1934463-10-1)
Recommended Standards
- (Z)-4-Ethoxy-1,1,1-trifluorobut-3-en-2-one (CAS 910136-24-2)
- 1,1,1-Trifluoro-3-methylpentane-2,4-dione (CAS 360-82-7)
- (E)-4,4,4-Trifluorobut-2-en-1-yl acetate (CAS 728040-39-9)
- 2-(2-(Trifluoromethyl)cyclopropyl)acetic acid (CAS 2167179-47-5)
- 146448-53-5 2-methyl-N-tosylbenzamide 4-Methyl-N-(2-methyl-benzoyl)benzenesulfonamide (CAS 146448-53-5)
- 3,3-DIMETHYLPYRROLIDINE-2-CARBOXYLIC ACID HCL (CAS 61406-78-8)
- (R)-3-Hydroxybutanoic Acid (CAS 625-72-9)
- Ethyl 5-hydroxy-2-phenylbenzofuran-3-carboxylate (CAS 4610-75-7)
- Methyl 3-methoxy-5-[4-(methoxycarbonyl)phenyl]benzoate (CAS 1820618-09-4)
- 7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one (CAS 55469-90-4)
- 2-(4-(Allyloxy)benzylidene)hydrazinecarboxamide (CAS 3256-36-8)
- 3,4-Dihydro-4-oxo-1-phthalazinecarboxamide (CAS 59908-31-5)
- Fenticonazole Impurity 7 (CAS CATO-C4X-24917)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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