cis-3-(trifluoromethyl)cyclobutanecarboxylic acid CAS 123812-82-8
| CAS No. | 123812-82-8 |
| Molecular Formula | C6H7F3O2 |
| Molecular Weight | 168.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of cis-3-(trifluoromethyl)cyclobutanecarboxylic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
cis-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 123812-82-8), molecular formula C6H7F3O2 and molecular weight 168.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, cis-3-(trifluoromethyl)cyclobutanecarboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 168.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), cis-3-(trifluoromethyl)cyclobutanecarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7F3O2 |
| Molecular Weight | 168.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related cis Standards
- 3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1093750-93-6)
- trans-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 123812-83-9)
- 2-[1-(Trifluoromethyl)cyclopropyl]acetic Acid (CAS 1368342-07-7)
- 2-(trifluoromethyl)furan-3-carbaldehyde (CAS 1378259-70-1)
- 5-(trifluoromethyl)furan-2-carbaldehyde (CAS 17515-80-9)
- 2-(Trifluoromethyl)dihydro-2H-pyran-4(3H)-one (CAS 1803611-31-5)
- 2-(Trifluoromethyl)cyclobutane-1-carboxylic acid (CAS 1934463-10-1)
- 1-(Trifluoromethyl)cyclobutanecarboxylic Acid (CAS 277756-45-3)
Recommended Standards
- 2,4-Dinitrosobenzene-1,3-diol (CAS 118-02-5)
- 2-(3-Chloro-2-fluorophenyl)pyrrolidine (CAS 1260802-03-6)
- 1-(2,2,2-Trifluoroethyl)cyclopropane-1-carboxylic acid (CAS 1026283-70-4)
- Pyrimidine-2,5-dicarboxylic acid (CAS 127527-24-6)
- Glupa-Carboxylate (CAS 53602-84-9)
- Ethyl (1S,2R,3R,5R)-2-((tert-butoxycarbonyl)amino)-6-oxabicyclo[3.1.0]hexane-3-carboxylate (CAS 959745-87-0)
- 1-Bromo-2-ethenyl-4,5-dimethoxybenzene (CAS 5293-43-6)
- 2-Cyclopentyl-4-oxazolecarboxylic Acid (CAS 1247889-30-0)
- 1-(3-Chloro-4-fluorophenyl)cyclobutanamine (CAS 1314791-33-7)
- Ethylenediaminetetraacetic Acid Magnesium Disodium Salt (CAS 14402-88-1)
- des-1-D-2Nal-Cetrorelix (CAS CATO-C4X-201459)
- 2-(1H-Benzo[d]imidazol-5-yl)-2-oxoacetaldehyde (CAS 124663-09-8)
- 2-Amino-6-Ethoxynaphthalene (CAS 293733-21-8)
- Semaglutide Impurity 6 (CAS 62-57-7)
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