3-((4-Chlorophenyl)carbamoyl)pyrazine-2-carboxylic acid CAS 278610-25-6
| CAS No. | 278610-25-6 |
| Molecular Formula | C12H8ClN3O3 |
| Molecular Weight | 277.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-((4-Chlorophenyl)carbamoyl)pyrazine-2-carboxylic acid.
CATO supplies 3-((4-Chlorophenyl)carbamoyl)pyrazine-2-carboxylic acid (CAS 278610-25-6), a certified reference material (molecular formula C12H8ClN3O3, MW 277.66 g/mol) for analytical method development and quality control.
Structurally, 3-((4-Chlorophenyl)carbamoyl)pyrazine-2-carboxylic acid (C12H8ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 277.66 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-((4-Chlorophenyl)carbamoyl)pyrazine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8ClN3O3 |
| Molecular Weight | 277.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 5-Amino-1-(4-methylbenzyl)-1h-1,2,3-triazole-4-carboxamide (CAS 99613-60-2)
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