3-(4-Chlorobenzamido)pyrazine-2-carboxylic acid CAS 294853-37-5
| CAS No. | 294853-37-5 |
| Molecular Formula | C12H8ClN3O3 |
| Molecular Weight | 277.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(4-Chlorobenzamido)pyrazine-2-carboxylic acid (C12H8ClN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-(4-Chlorobenzamido)pyrazine-2-carboxylic acid (CAS 294853-37-5), a certified reference material (molecular formula C12H8ClN3O3, MW 277.66 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(4-Chlorobenzamido)pyrazine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClN3O3 |
| Molecular Weight | 277.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorobenzamido Standards
- 4-(4-Chlorobenzamido)-1-methyl-1H-pyrrole-2-carboxylic acid (CAS 478804-04-5)
- 5-(3-Chlorobenzamido)-2-methoxypyridin-1-ium-1-olate (CAS 400074-19-3)
- 5-(4-Chlorobenzamido)-2-methoxypyridin-1-ium-1-olate (CAS 860787-86-6)
- 2-(2-Chlorobenzamido)benzoic acid (CAS 31408-56-7)
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Recommended Standards
- 3-((4-Chlorophenyl)carbamoyl)pyrazine-2-carboxylic acid (CAS 278610-25-6)
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- 2-Chloro-N-(5-nitropyridin-2-yl)benzamide (CAS 549484-69-7)
- 4-(2-Chlorophenoxy)-3-nitrobenzaldehyde (CAS 338403-42-2)
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- Methyl 3-(6-methylnicotinamido)propanoate (CAS 1100163-64-1)
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