4,4'-Methylenebis[2-chlorophenol] CAS 2787-77-1
| CAS No. | 2787-77-1 |
| Molecular Formula | C13H22Cl2O2 |
| Molecular Weight | 281.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,4'-Methylenebis[2-chlorophenol] is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4,4'-Methylenebis[2-chlorophenol] (CAS 2787-77-1) is a high-purity analytical reference standard with the molecular formula C13H22Cl2O2 and a molecular weight of 281.22 g/mol.
The molecular framework of 4,4'-Methylenebis[2-chlorophenol] (C13H22Cl2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,4'-Methylenebis[2-chlorophenol] under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H22Cl2O2 |
| Molecular Weight | 281.22 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Methylenebis Standards
- 4,4'-Methylenebis(2-allylphenol) (CAS 62386-37-2)
- 4,4'-Methylenebis(2-ethyl-3-methylaniline) (CAS 1632285-94-9)
- 4,4'-Methylenebis(2-ethyl-6-methylaniline) (CAS 19900-72-2)
- 5,5'-(Methylenebis(azanediyl))bis(1,3,4-thiadiazole-2(3H)-thione) (CAS 79319-85-0)
- 2,2'-((Methylenebis(oxy))bis(methylene))bis(2-(hydroxymethyl)propane-1,3-diol) (CAS 6228-26-8)
- 1,1'-(Methylenebis(2-hydroxy-5,1-phenylene))diethanone (CAS 28467-22-3)
- 5,5'-Methylenebis(2-aminobenzoic acid) (CAS 7330-46-3)
- Methylenebis[dimethyl(2-pyridyl)silane] (CAS 243468-48-6)
Recommended Standards
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