3-(1-Piperidinyl)aniline CAS 27969-75-1
| CAS No. | 27969-75-1 |
| Molecular Formula | C11H16N2 |
| Molecular Weight | 176.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(1-Piperidinyl)aniline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(1-Piperidinyl)aniline (CAS 27969-75-1), molecular formula C11H16N2 and molecular weight 176.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(1-Piperidinyl)aniline (C11H16N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(1-Piperidinyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16N2 |
| Molecular Weight | 176.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 2 |
Related Piperidinyl Standards
- 4-(4-Methyl-4-piperidinyl)pyridine (CAS 1342973-21-0)
- 3-(4-Methyl-4-piperidinyl)pyridine (CAS 1343593-92-9)
- 2-(1-Piperidinyl)-3-pyridinamine (CAS 5028-14-8)
- 5-(1-Piperidinyl)-3-pyridazinol (CAS 82226-41-3)
- 1-[8-[1-oxo-2-(1-piperidinyl)ethyl]-2-dibenzofuranyl]-2-(1-piperidinyl)ethanone dihydrochloride 2-piperidin-1-yl-1-[8-(2-piperidin-1-ylethanoyl)dibenzofuran-2-yl]ethanone dihydrochloride 40870-59-5 A825326 (CAS 40870-59-5)
- 3-(1-Piperidinyl)-D-Ala-OH (CAS 2044710-80-5)
- 3-(1-Piperidinyl)-L-Ala-OH (CAS 911633-41-5)
- 2-(4-Piperidinyl)ethyl propyl ether (CAS 688736-47-2)
Recommended Standards
- 2-Phenylpiperidin-3-amine (CAS 58373-46-9)
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- 2-N-Cyclopentylbenzene-1,2-diamine (CAS 600725-69-7)
- 3-(Isoindolin-2-yl)propan-1-amine (CAS 21507-93-7)
- 2,6-Difluoro-3-hydroxybenzamide (CAS 951122-37-5)
- (S)-Methyl indoline-2-carboxylate hydrochloride (CAS 96056-64-3)
- 5-(Methylthio)thiazole (CAS 40982-34-1)
- Methyl-Pentachlorophenyl Sulfide (CAS 1825-19-0)
- 2-(2-Chloro-6-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1061367-22-3)
- 2-(((Benzyloxy)carbonyl)amino)-3-(trifluoromethyl)cyclopropane-1-carboxylic acid (CAS 1240526-66-2)
- 1-(2-(1h-1,2,4-Triazol-1-yl)ethyl)-5-aminopyridin-2(1h)-one (CAS 1094892-30-4)
- 5-(Bromomethyl)-1-methyl-1H-indole (CAS 1936732-18-1)
- 2-Cyclopropyl-2-phenylethan-1-amine (CAS 112093-23-9)
- Des-Ser32-Tirzepatide (CAS CATO-CPTD788942)
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