3-(2,2-difluoroethyl)-1-{7H-pyrrolo[2,3-d]pyrimidine-6-carbonyl}piperidine CAS 2797795-70-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2797795-70-9
Molecular FormulaC14H16F2N4O
Molecular Weight294.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2,2-difluoroethyl)-1-{7H-pyrrolo[2,3-d]pyrimidine-6-carbonyl}piperidine CAS 2797795-70-9 chemical structure

Description

The occurrence of 3-(2,2-difluoroethyl)-1-{7H-pyrrolo[2,3-d]pyrimidine-6-carbonyl}piperidine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-(2,2-difluoroethyl)-1-{7H-pyrrolo[2,3-d]pyrimidine-6-carbonyl}piperidine (CAS 2797795-70-9), molecular formula C14H16F2N4O and molecular weight 294.30 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(2,2-difluoroethyl)-1-{7H-pyrrolo[2,3-d]pyrimidine-6-carbonyl}piperidine (C14H16F2N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H16F2N4O
Molecular Weight294.30 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Halogen ContentF-containing
Nitrogen Atoms4

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