[(2R,4R)-4-[2-Amino-6-(cyclopropylamino)purin-9-yl]-1,3-dioxolan-2-yl]methanol CAS 280138-71-8
| CAS No. | 280138-71-8 |
| Molecular Formula | C12H24N6O3 |
| Molecular Weight | 300.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 300.36 g/mol gives [(2R,4R)-4-[2-Amino-6-(cyclopropylamino)purin-9-yl]-1,3-dioxolan-2-yl]methanol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
[(2R,4R)-4-[2-Amino-6-(cyclopropylamino)purin-9-yl]-1,3-dioxolan-2-yl]methanol (CAS 280138-71-8), molecular formula C12H24N6O3 and molecular weight 300.36 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, [(2R,4R)-4-[2-Amino-6-(cyclopropylamino)purin-9-yl]-1,3-dioxolan-2-yl]methanol (C12H24N6O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 300.36 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), [(2R,4R)-4-[2-Amino-6-(cyclopropylamino)purin-9-yl]-1,3-dioxolan-2-yl]methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H24N6O3 |
| Molecular Weight | 300.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 6 |
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