Rivaroxaban Impurity 102 CAS 28025-61-8
| CAS No. | 28025-61-8 |
| Molecular Formula | C10H12ClNO2 |
| Molecular Weight | 213.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Rivaroxaban Impurity 102 (CAS 28025-61-8), a pharmacopoeial impurity reference standard (molecular formula C10H12ClNO2, MW 213.66 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Rivaroxaban Impurity 102 (C10H12ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 213.66 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Rivaroxaban Impurity 102 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO2 |
| Molecular Weight | 213.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 62 (CAS 89283-13-6)
- Rivaroxaban Impurity 122 (CAS 89281-29-8)
- Rivaroxaban Impurity 52 (CAS CATO-C4X-109052)
- Rivaroxaban Impurity 87 (CAS CATO-C4X-109087)
- Rivaroxaban Impurity 105 (CAS 1261222-08-5)
- Rivaroxaban Impurity 107 (CAS 482308-13-4)
- Rivaroxaban Impurity 81 (CAS 1394169-92-6)
- Rivaroxaban Impurity 49 (CAS 1224684-98-3)
Recommended Standards
- (R)-Baclofen (CAS 69308-37-8)
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- Lidocaine impurity 64 (CAS 64585-19-9)
- Finerenone Impurity 92 (CAS CATO-C4X-288092)
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- Lumefentrine Keto Impurity (CAS 53221-25-3)
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- tert-Butyl 6'-chlorospiro[azetidine-3,3'-indoline]-1'-carboxylate (CAS 1403899-32-0)
- 2-(N-acetylacetamido)-3-(4-hydroxy-3-methoxyphenyl)propanoic acid (CAS 63357-45-9)
- 4-Bromo-6-(difluoromethyl)-5-(trifluoromethyl)picolinaldehyde (CAS 1804494-57-2)
- 2-Cyano-3-(2,5-dimethoxyphenyl)-N-(2-ethylphenyl)propanamide (CAS 1260997-41-8)
- Biotinyl-Neuropeptide W-23 (human) (CAS 1815618-09-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com