(2R,4R)-4-Fluoro-2-(methoxymethyl)-1-methyl-2-pyrrolidinemethanol CAS 2803283-22-7
| CAS No. | 2803283-22-7 |
| Molecular Formula | C8H16FNO2 |
| Molecular Weight | 177.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(2R,4R)-4-Fluoro-2-(methoxymethyl)-1-methyl-2-pyrrolidinemethanol (CAS 2803283-22-7) is a high-purity analytical reference standard with the molecular formula C8H16FNO2 and a molecular weight of 177.22 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (2R,4R)-4-Fluoro-2-(methoxymethyl)-1-methyl-2-pyrrolidinemethanol is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 177.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), (2R,4R)-4-Fluoro-2-(methoxymethyl)-1-methyl-2-pyrrolidinemethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H16FNO2 |
| Molecular Weight | 177.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
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- 4-(3-Fluorophenyl)-1,2,3,6-tetrahydropyridine (CAS 1978-60-5)
- (R)-N-Boc-1-fluoro-2-propylamine (CAS 2006287-03-0)
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- (S)-3-(2-Methylphenoxy)pyrrolidine hydrochloride (CAS 900512-43-8)
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- Methyl 2-(2-amino-3-methoxyphenyl)acetate (CAS 1261855-04-2)
- 7-Bromo-1-methyl-2,3-dihydro-1H-indol-2-one (CAS 100831-25-2)
- 1-(4-cyclobutylphenyl)ethan-1-one (CAS 6921-50-2)
- Diethyl 4-Ethoxypyridine-2,6-dicarboxylate (CAS 18986-18-0)
- (2-(6-Hydroxypyridin-3-yl)phenyl)(pyrrolidin-3-yl)methanone (CAS 1261896-01-8)
- 8-Chloro-2-(furan-2-yl)quinoline-4-carboxylic acid (CAS 52413-55-5)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
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