3-Amino-N-(3-chloro-4-fluorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide CAS 445269-00-1
| CAS No. | 445269-00-1 |
| Molecular Formula | C20H19ClFN3OS |
| Molecular Weight | 403.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-N-(3-chloro-4-fluorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-N-(3-chloro-4-fluorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 445269-00-1) is a high-purity analytical reference standard with the molecular formula C20H19ClFN3OS and a molecular weight of 403.90 g/mol.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 3-Amino-N-(3-chloro-4-fluorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 403.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Amino-N-(3-chloro-4-fluorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H19ClFN3OS |
| Molecular Weight | 403.90 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-N-(2-chloro-4-fluorophenyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 625370-22-1)
- 3-Amino-N-(4-chloro-2-fluorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 627056-91-1)
- 2-((4-Amino-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxy-5-methylphenyl)acetamide (CAS 763108-71-0)
- 2-((4-Amino-5-(4-chlorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxy-5-methylphenyl)acetamide (CAS 713099-80-0)
- (R)-2-((6-((3-Amino-5-chlorophenyl)amino)-9-isopropyl-9H-purin-2-yl)amino)-3-methylbutan-1-ol (CAS 220792-57-4)
- 5-((5-Amino-2-chlorophenyl)imino)-2-(2,4,6-trichlorophenyl)pyrazolidin-3-one (CAS 53411-33-9)
- 3-Amino-N-(4-iodo-phenyl)-4-methoxy-benzenesulfonamide (CAS 379726-54-2)
- 5-Amino-N-(4-iodophenyl)-2-methoxybenzene-1-sulfonamide (CAS 438031-73-3)
Recommended Standards
- 3-{[2-chloro-6-(1H-indol-1-yl)phenyl]methyl}-1-(2,6-dimethylphenyl)urea (CAS 866042-70-8)
- 5-(4-Butoxyphenyl)-2-(4-chlorophenyl)-3H-benzo[e][1,2,4]triazepine (CAS 444153-16-6)
- 3-(4-Butoxyphenyl)-5-(4-chlorophenyl)-4-phenyl-4H-1,2,4-triazole (CAS 444153-36-0)
- 7-(4-Chlorophenyl)-N-(2,6-dimethylphenyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxamide (CAS 338419-66-2)
- Xylotuberin (CAS 64526-29-0)
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- 5-(Bromomethyl)-2-(4-ethoxyphenyl)-4,5-dihydrothiazole hydrobromide (CAS 1051941-60-6)
- 5-Bromo-N-(2-(imidazo[2,1-b]thiazol-6-yl)ethyl)furan-2-carboxamide (CAS 868980-40-9)
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- 2-(pyrimidin-2-ylsulfanyl)-1,3-oxazole-4-carboxylic acid (CAS 1566207-10-0)
- Sperm Activating Peptide, Sea Urchin (CAS 140653-27-6)
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