4-(4-aminopiperidin-1-yl)benzonitrile CAS 281234-90-0
| CAS No. | 281234-90-0 |
| Molecular Formula | C12H15N3 |
| Molecular Weight | 201.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, 4-(4-aminopiperidin-1-yl)benzonitrile is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 201.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(4-aminopiperidin-1-yl)benzonitrile (CAS 281234-90-0), molecular formula C12H15N3 and molecular weight 201.27 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15N3 |
| Molecular Weight | 201.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related aminopiperidin Standards
- 2-(4-Aminopiperidin-1-yl)benzonitrile (CAS 1039022-11-1)
- 2-(3-Aminopiperidin-1-yl)benzonitrile (CAS 1248981-76-1)
- 6-(4-Aminopiperidin-1-yl)hexan-1-ol (CAS 1098627-74-7)
- 2-(4-Aminopiperidin-1-yl)nicotinonitrile (CAS 412355-86-3)
- 6-(4-Aminopiperidin-1-yl)pyridine-3-carbonitrile (CAS 252577-87-0)
- Methyl 3-(3-aminopiperidin-1-yl)butanoate (CAS 1248455-31-3)
- 5-(4-Aminopiperidin-1-yl)pentanoic acid (CAS 1250399-50-8)
- 3-(3-Aminopiperidin-1-yl)-2,2-dimethylpropanoic acid (CAS 1539913-01-3)
Recommended Standards
- 4-(2-Isopropyl-1H-imidazol-1-yl)aniline (CAS 745737-06-8)
- 4-(4-Isopropylphenyl)-1H-pyrazol-5-amine (CAS 941573-49-5)
- 4-(2-hydrazinylpyrimidin-4-yl)morpholine (CAS 908141-95-7)
- 4-(4-Methylpiperazin-1-yl)benzonitrile (CAS 34334-28-6)
- [3,5-bis(aminomethyl)phenyl]methanamine trihydrobromide (CAS 1864060-71-8)
- 81-83-4 GI0TV19GBN Naphthalimide 1H-Benz(de)isoquinoline-1,3(2H)-dione Naphthalene-1,8-dicarboximide Naphthalimide (8CI) EINECS 201-379-7 1,8-Naphthalenedicarboximide 1,8-Naphthalimide NSC 11011 UNII-GI0TV19GBN EC 201-379-7 (CAS 81-83-4)
- 4-Chloro-2,6-dimethylnicotinic acid (CAS 56022-09-4)
- 4-Methylumbelliferyl p-trimethylammoniocinnamate chloride (CAS 34197-47-2)
- (S)-7-nitro-1,2,3,4,4a,5-hexahydrobenzo[b]pyrazino[1,2-d][1,4]oxazine hydrochloride (CAS CATO-C3D-262481)
- 2,2'-Bis(methoxymethoxy)-1,1'-biphenyl (CAS 121169-22-0)
- 2,3-Dihydro-1h-indene-2-sulfonamide (CAS 1251381-40-4)
- 3-Methyl-1-octyl-1H-imidazol-3-ium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate (CAS 905972-83-0)
- 2-(Benzylthio)-1-(2,4-dichloro-5-(2-methoxyethoxy)phenyl)-1H-imidazole (CAS 338967-20-7)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
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