2-(4-Aminopiperidin-1-yl)nicotinonitrile CAS 412355-86-3
| CAS No. | 412355-86-3 |
| Molecular Formula | C11H14N4 |
| Molecular Weight | 202.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Aminopiperidin-1-yl)nicotinonitrile.
CATO supplies 2-(4-Aminopiperidin-1-yl)nicotinonitrile (CAS 412355-86-3), a certified reference material (molecular formula C11H14N4, MW 202.26 g/mol) for analytical method development and quality control.
Structurally, 2-(4-Aminopiperidin-1-yl)nicotinonitrile (C11H14N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 202.26 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14N4 |
| Molecular Weight | 202.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Aminopiperidin Standards
- 6-(4-Aminopiperidin-1-yl)pyridine-3-carbonitrile (CAS 252577-87-0)
- 2-(4-Aminopiperidin-1-yl)benzonitrile (CAS 1039022-11-1)
- 2-(3-Aminopiperidin-1-yl)benzonitrile (CAS 1248981-76-1)
- 4-(4-aminopiperidin-1-yl)benzonitrile (CAS 281234-90-0)
- 6-(4-Aminopiperidin-1-yl)hexan-1-ol (CAS 1098627-74-7)
- Methyl 3-(3-aminopiperidin-1-yl)butanoate (CAS 1248455-31-3)
- 5-(4-Aminopiperidin-1-yl)pentanoic acid (CAS 1250399-50-8)
- 3-(3-Aminopiperidin-1-yl)-2,2-dimethylpropanoic acid (CAS 1539913-01-3)
Recommended Standards
- 2-(4-(Pyridin-4-ylmethyl)-1H-imidazol-5-yl)ethanamine (CAS 769912-44-9)
- 2-(Piperidin-4-yl)-1H-imidazo[4,5-b]pyridine (CAS 578709-10-1)
- 2-(4-(Prop-2-yn-1-yl)piperazin-1-yl)pyrimidine (CAS 922723-25-9)
- 2-(Piperidin-4-yl)-3H-imidazo[4,5-c]pyridine (CAS 578709-09-8)
- BD 1008-d5 Dihydrobromide (CAS 1246817-16-2)
- P-tolylmethanethiol (CAS 4498-99-1)
- 3,3-Dimethyl-1-(2-nitro-4-(trifluoromethyl)phenyl)azetidin-2-one (CAS 861881-16-5)
- Salbutamol Impurity 131 (CAS CATO-C4X-1176131)
- N-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine (CAS 1218789-33-3)
- N-(4,6-Difluoro-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)isoxazole-5-carboxamide (CAS 1006998-87-3)
- 4-[4-Methyl-2-(pyridin-3-yl)-1,3-thiazol-5-yl]pyrimidin-2-amine (CAS 1055069-00-5)
- 2'-Bromo-[1,1'-biphenyl]-4-carbaldehyde (CAS 198205-81-1)
- 1-[2-Bromovinyl]-4-fluorobenzene (CAS 870122-74-0)
- Neuropeptide GE (CAS 134748-04-2)
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